Mouse CXCL1/KC ELISA Kit ( EM0017)
Catalog# EM0017
Assay type Sandwich ELISA
Range 13.72~10000 pg/ml
Sensitivity 2.11 pg/ml (10 μl)
PERFORMANCE CHARACTERISTICS
Sensitivity
2.11 pg/ml (10 μl)
Range
13.72~10000 pg/ml
Recovery
The spike recovery was evaluated by spiking 3 levels of mouse CXCL1/KC into health mouse serum sample. The un-spiked serum was used as blank in this experiment. The recovery ranged from 88% to 109% with an overall mean recovery of 96%.
Specifications
Product Type
ELISA Kit
Product Name
Mouse CXCL1/KC ELISA Kit ( EM0017)
Detection method
Colorimetric
Sample type
Serum
Assay type
Sandwich ELISA
Category
Fully Ready-to-Use
PROPERTIES
Storage instructions
Store at +4C
Kits Components
Coated Plate
96 well
Standard
9 vial
Detect Antibody
6 ml/bottle
Streptavidin-HRP
12 ml/bottle
Assay Buffer
12 ml/bottle
Stop Solution
12 ml/bottle
Wash Buffer
50 ml/bottle
Sealer Film
6 pieces
TARGET
UNIPROT #
PROTEIN NAME
CXCL1/KC
FUNCTION
CXCL1/GRO alpha, also known as KC in mouse and CINC-1 in rat, is a member of the CXC family of chemokines. Human CXCL1/GRO alpha is 107 amino acids (aa) in length with a predicted molecular weight of 11 kDa. The mouse and rat orthologs share 57% and 59% amino acid sequence identity with the human protein, respectively. Genome-wide analysis suggests that the protein encoded by the mouse Cxcl3 gene is homologous to human CXCL1/GRO alpha protein. Human CXCL1/GRO alpha can be cleaved into three isoforms CXCL1/GRO alpha (aa 4-73), CXCL1/GRO alpha (aa 5-73), and CXCL1/GRO alpha (aa 6-73) which show higher activity than the full length protein. CXCL1/GRO alpha is secreted by mast cells and macrophages whereupon it acts as a chemoattractant for neutrophils.
CITATIONS
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Fuxiang Li,et al
SIRT7 remodels the cytoskeleton via RAC1 to enhance host resistance to Mycobacterium tuberculosis
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Elisa
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Mouse;Human
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Citation
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