NCOR2/SMRT Rabbit Polyclonal Antibody (HA500226)

UNIPROT #

Q9Y618

PROTEIN NAME

NCOR2/SMRT

SYNONYMS

CTG 26 antibody;CTG repeat protein 26 antibody;CTG26 antibody;N CoR2 antibody;N-CoR2 antibody;NCoR 2 antibody;Ncor2 antibody;NCOR2_HUMAN antibody;Nuclear Receptor Co-Repressor 2 antibody;Nuclear receptor corepressor 2 antibody;retinoic-acid-receptor-associated corepressor antibody;Silencing Mediator for Retanoid and Thyroid Hormone Receptors antibody;Silencing mediator of retinoic acid and thyroid hormone receptor antibody;SMAP 270 antibody;SMAP270 antibody;SMRT antibody;SMRTE antibody;SMRTE tau antibody;T3 receptor associating factor antibody;T3 receptor-associating factor antibody;Thyroid retinoic acid receptor associated corepressor antibody;Thyroid- antibody;TNRC 14 antibody;TNRC14 antibody;TRAC 1 antibody;TRAC antibody;TRAC1 antibody

SUBCELLULAR LOCATION

Nucleus.

FUNCTION

SMRT / NCoR2 (Nuclear receptor corepressor 2, CTG repeat protein 26, SMAP270, Silencing mediator of retinoic acid and thyroid hormone receptor, Thyroid and retinoic-acid-receptor-associated corepressor, TRAC) is a transcriptional corepressor for nuclear receptors. SMRT / NCoR2 has been shown to play a role in regulating immune response, mediating DNA repair, and in neuronal differentiation and cardiac development. SMRT / NCoR2 is part of a large corepressor complex that contains SIN3A/B and histone deacetylases HDAC1 and HDAC2.