NME2 Recombinant Rabbit Monoclonal Antibody [JE40-86] (HA722553)

UNIPROT #

P22392

PROTEIN NAME

NME2

SYNONYMS

C myc purine binding transcription factor PUF antibody;C myc transcription factor antibody;C-myc purine-binding transcription factor PUF antibody;epididymis secretory sperm binding protein Li 155an antibody;HEL-S-155an antibody;Histidine protein kinase NDKB antibody;MGC111212 antibody;MGC2212 antibody;NDK B antibody;NDKB antibody;NDKB_HUMAN antibody;NDP kinase B antibody;NDPK B antibody;NDPKB antibody;NM23 H2 antibody;nm23-H2 antibody;NM23B antibody;NME/NM23 nucleoside diphosphate kinase 2 antibody;nme2 antibody;Non metastatic cells 2, protein (NM23B) expressed in antibody;non-metastatic cells 2, protein (NM23) expressed in antibody;Nucleoside diphosphate kinase B antibody;Nucleotide diphosphate kinase B antibody;PUF antibody

SUBCELLULAR LOCATION

Cytoplasm, Cell projection, lamellipodium, ruffle.

FUNCTION

Nucleoside diphosphate kinase B is an enzyme that in humans is encoded by the NME2 gene. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. Co-transcription of this gene and the neighboring upstream gene (NME1) generates naturally occurring transcripts (NME1-NME2) which encode a fusion protein consisting of sequence sharing identity with each individual gene product.