Phosphotyrosine Recombinant Rabbit Monoclonal Antibody [JA10-49] (ET1704-20)
Catalog# ET1704-20
Rabbit Monoclonal to Phosphotyrosine
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WB
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IF-Cell
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IF-Tissue
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IP
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FC
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Species independent
Specifications
Product Type
Recombinant Rabbit monoclonal primary
Product Name
Phosphotyrosine Recombinant Rabbit Monoclonal Antibody [JA10-49] (ET1704-20)
Immunogen
Cxxxx-py-xxxxnh2.
Host
Rabbit
Positive Control
A431 cells lysates treated with Sodium metavanadate.
Conjugation
Unconjugated
Clonality
Monoclonal
Clone Number
JA10-49
RRID
APPLICATION DILUTION
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WB
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1:50-1:200
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FC
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1:10-1:50
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IF-Cell
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1:50
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IF-Tissue
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1:50
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1ug/ul
Purification
Protein A affinity purified.
Isotype
IgG
TARGET
PROTEIN NAME
Phosphotyrosine
FUNCTION
Tyrosine phosphorylation plays a key role in cellular signaling. Research studies have shown that in cancer, unregulated tyrosine kinase activity can drive malignancy and tumor formation by generating inappropriate proliferation and survival signals. Antibodies specific for phospho-tyrosine have been invaluable reagents in these studies. The phospho-tyrosine monoclonal antibodies developed by Cell Signaling Technology are exceptionally sensitive tools for studying tyrosine phosphorylation and monitoring tyrosine kinase activity in high throughput drug discovery.
CITATIONS
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Cheng, J., Yu, Y., Wang, X., Zheng, X., Liu, T., Hu, D., Jin, Y., Lai, Y., Fu, T. M., & Chen, Q.
Structural basis for the self-recognition of sDSCAM in Chelicerata
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WB
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Citation
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