Protein CASP Mouse Monoclonal Antibody [A9F6] (HA601128)

UNIPROT #

Q13948

PROTEIN NAME

Protein CASP

SYNONYMS

CASP_HUMAN antibody;CUX1 antibody;Protein CASP antibody;CCAAT displacement protein antibody;CDP antibody;CDP/Cut antibody;CDP1 antibody;Clox antibody;COY1 antibody;Cut homeobox antibody;Cut homolog antibody;Cut like 1 antibody;Cut like homeobox 1 antibody;CUTL1 antibody;CUX antibody;Cux/CDP antibody;CUX1 antibody;Golgi integral membrane protein 6 antibody;GOLIM6 antibody;Homeobox protein cux 1 antibody;Nbla10317 antibody;p100 antibody;p110 antibody;p200 antibody;p75 antibody;Putative protein product of Nbla10317 antibody

SUBCELLULAR LOCATION

Golgi apparatus membrane.

FUNCTION

CUX1 is an animal gene. The name stands for Cut like homeobox 1. The term "cut" derives from the "cut wing" phenotype observed in a mutant of Drosophila melanogaster. In mammals, a CCAAT-displacement activity was originally described in DNA binding assays. The human gene was identified following purification of the CCAAT-displacement protein (CDP) and has been successively been called CDP, Cut-like 1 (CUTL1), CDP/Cut and finally, CUX1. (Consequently, a literature search for CUX1 fails to bring up many of the earlier studies). Cut homeobox genes are present in all metazoans. In mammals, CUX1 is expressed ubiquitously in all tissues. A second gene, called CUX2, is expressed primarily in neuronal cells.