PSD93 Recombinant Rabbit Monoclonal Antibody [JM41-04] (ET1705-90)
Catalog# ET1705-90
Rabbit Monoclonal to PSD93
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WB
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FC
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IP
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Human
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Mouse
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Rat
Positive control:
Lane 1: Hela cell lysate
Lane 2: SH-SY5Y cell lysate
Specifications
Product Type
Recombinant Rabbit monoclonal primary
Product Name
PSD93 Recombinant Rabbit Monoclonal Antibody [JM41-04] (ET1705-90)
Immunogen
Synthetic peptide within human psd93 aa 600-660.
Host
Rabbit
Positive Control
Hela cell lysate, SH-SY5Y cell lysate, SH-SY5Y.
Conjugation
Unconjugated
Clonality
Monoclonal
Clone Number
JM41-04
RRID
APPLICATION DILUTION
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WB
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1:500-1:2,000
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FC
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1:50-1:100
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IP
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Use at an assay dependent concentration.
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1ug/ul
Purification
Protein A affinity purified.
Molecular Weight
Predicted band size: 98 kDa
Isotype
IgG
TARGET
UNIPROT #
PROTEIN NAME
PSD93
SYNONYMS
Channel associated protein of synapse 110 antibody;Channel associated protein of synapses 110kD antibody;Channel-associated protein of synapse-110 antibody;Chapsyn 110 antibody;Chapsyn-110 antibody;Chapsyn110 antibody;Discs, large homolog 2 (Drosophila) antibody;Disks large homolog 2 antibody;DKFZp781D1854 antibody;DKFZp781E0954 antibody;Dlg 2 antibody;dlg2 antibody;DLG2_HUMAN antibody;Dlgh 2 antibody;Dlgh2 antibody;FLJ37266 antibody;Gm1197 antibody;MGC131811 antibody;Postsynaptic density protein PSD 93 antibody;Postsynaptic density protein PSD-93 antibody;Postsynaptic density protein PSD93 antibody;PSD 93 antibody;PSD93 antibody
SEQUENCE SIMILARITIES
Belongs to the MAGUK family.
POST-TRANSLATIONAL MODIFICATION
Palmitoylation of isoform 1 is not required for targeting to postsynaptic density.
SUBCELLULAR LOCATION
Cell junction, Cell membrane, Cell projection, Membrane, Synapse.
FUNCTION
Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses.
CITATIONS
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Effects of fibroblast growth factor 21 on lactate uptake and usage in mice with diabetes-associated cognitive decline
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WB
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Mouse
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Citation
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