ROR2 Recombinant Rabbit Monoclonal Antibody [JE37-72] (HA721417)

UNIPROT #

Q01974

PROTEIN NAME

ROR2

SYNONYMS

BDB antibody;BDB1 antibody;Brachydactyly type B antibody;EC 2.7.10.1 antibody;MGC163394 antibody;Neurotrophic tyrosine kinase antibody;Neurotrophic tyrosine kinase, receptor related 2 antibody;NTRKR2 antibody;Receptor tyrosine kinase-like orphan receptor 2 antibody;receptor-related 2 antibody;ROR2 antibody;ROR2_HUMAN antibody;Tyrosine protein kinase transmembrane receptor ROR2 antibody;Tyrosine-protein kinase transmembrane receptor Ror2 antibody

SUBCELLULAR LOCATION

Cell membrane.

FUNCTION

Tyrosine-protein kinase transmembrane receptor ROR2, also known as neurotrophic tyrosine kinase, receptor-related 2, is a protein that in humans is encoded by the ROR2 gene located on position 9 of the long arm of chromosome 9. This protein is responsible for aspects of bone and cartilage growth. It is involved in Robinow syndrome and autosomal dominant brachydactyly type B. ROR2 is a member of the receptor tyrosine kinase-like orphan receptor (ROR) family. The protein encoded by this gene is a receptor tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development.