RRAS2 Rabbit Polyclonal Antibody (HA500379)
Catalog# HA500379
Rabbit Polyclonal to RRAS2
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WB
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IHC-P
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Human
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Mouse
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Rat
Lane 1: SKOV-3 cell lysate
Lane 2: NIH/3T3 cell lysate
Lane 3: PC-12 cell lysate
Lysates/proteins at 10 µg/Lane.
Predicted band size: 23 kDa
Observed band size: 23 kDa
Exposure time: 2 minutes;
12% SDS-PAGE gel.
Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (HA500379) at 1/1,000 dilution was used in 5% NFDM/TBST at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:300,000 dilution was used for 1 hour at room temperature.
Specifications
Product Type
Rabbit polyclonal primary
Product Name
RRAS2 Rabbit Polyclonal Antibody (HA500379)
Immunogen
Recombinant protein within human rras2 aa 2-201.
Host
Rabbit
Positive Control
SKOV-3 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, mouse testis tissue.
Conjugation
Unconjugated
Clonality
Polyclonal
RRID
APPLICATION DILUTION
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WB
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1:1,000
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IHC-P
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1:800
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
Storage Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2.1ug/ul
Purification
Immunogen affinity purified.
Molecular Weight
Predicted band size: 23 kDa
Isotype
IgG
TARGET
UNIPROT #
PROTEIN NAME
RRAS2
SYNONYMS
C86394 antibody;Oncogene RRAS2 antibody;Oncogene TC21 antibody;Ras like protein TC21 antibody;Ras related protein R Ras2 antibody;Ras-like protein TC21 antibody;Ras-related protein R-Ras2 antibody;Related RAS viral (r ras) oncogene homolog 2 antibody;Related RAS viral oncogene homolog 2 antibody;RRAS 2 antibody;RRAS2 antibody;RRAS2_HUMAN antibody;TC 21 antibody;TC21 antibody;Teratocarcinoma oncogene antibody;Teratocarcinoma oncogene TC21 antibody
SUBCELLULAR LOCATION
Cell membrane, Golgi apparatus membrane.
FUNCTION
It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion. Ubiquitously present in all tissues examined, with the highest levels in heart, placenta, and skeletal muscle. Moderate levels in lung and liver; low levels in brain, kidney, and pancreas. This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of certain tumors. Pseudogenes of this gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants.
CITATIONS
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Xu Yuanyuan,et al
Loss of SIL1 Affects Actin Dynamics and Leads to Abnormal Neural Migration
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WB
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Mouse
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Citation
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