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SCAI Mouse Monoclonal Antibody [7-A4] (M1004-5)

Price: Regular price $350.00

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Catalog# M1004-5

Mouse Monoclonal to SCAI

Tested for

  • WB

  • IF-Cell

  • IHC-P

Reacts with

  • Human

Specifications

Product Type

Mouse monoclonal primary

Product Name

SCAI Mouse Monoclonal Antibody [7-A4] (M1004-5)

Immunogen

Recombinant protein within human scai aa 1-606 / 606.

Host

Mouse

Positive Control

Recombinant protein, SHG-44, SH-SY-5Y, PC-12, human tonsil tissue, human lung tissue, human liver tissue, human brain tissue, human heart tissue, human pancreas tissue, human colon tissue

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

7-A4

RRID

AB_3073010

APPLICATION DILUTION

  • WB

  • 1:1,000-1:2,000

  • IF-Cell

  • 1:50-1:200

  • IHC-P

  • 1:50-1:400

PROPERTIES

Form

Liquid

Storage Condition

Store at -20C. Stable for 12 months from date of receipt.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

2ug/ul

Purification

Protein L affinity purified.

Molecular Weight

Predicted band size: 70 kDa

Isotype

IgM

TARGET

UNIPROT #

Q8N9R8

PROTEIN NAME

SCAI

SYNONYMS

C9orf126 antibody;FLJ11758 antibody;FLJ36664 antibody;MGC120525 antibody;MGC120526 antibody;MGC120528 antibody;NET40 antibody;Protein SCAI antibody;SCAI antibody;SCAI_HUMAN antibody;Suppressor of cancer cell invasion antibody;Suppressor of cancer cell invasion protein antibody

SEQUENCE SIMILARITIES

Belongs to the SCAI family.

SUBCELLULAR LOCATION

Membrane. Nucleus. Cytoplasm.

FUNCTION

Protein SCAI, also known as Suppressor of cancer cell invasion protein, and encoded by the gene name SCAI, is a tumor suppressor that suppresses MKL1-induced SRF transcriptional activity. It is a regulator of cell migration and appears to be involved in the RhoA (ras homolog gene family, member A)-Dia1 (diaphanous homolog 1) signal transduction pathway. SCAI localizes in the nucleus, where it binds and inhibits the myocardin-related transcription factor MAL by forming a ternary complex with serum response factor (SRF).

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