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SLC31A1 Recombinant Rabbit Monoclonal Antibody [JE56-93] (HA720005)

Price: Regular price $385.00

Volume

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Catalog# HA720005

Rabbit Monoclonal to SLC31A1

Tested for

  • WB

Reacts with

  • Human

  • Mouse

  • Rat

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free
This product has been cited in peer reviewed publications, see list HERE

Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

SLC31A1 Recombinant Rabbit Monoclonal Antibody [JE56-93] (HA720005)

Immunogen

Recombinant protein within human slc31a1 aa 1-82.

Host

Rabbit

Positive Control

SW480 cell lysate, A549 cell lysate, HepG2 cell lysate, SKOV-3 cell lysate, 293 cell lysate, HCT116 cell lysate, Neuro-2a cell lysate, C6 cell lysate, Mouse liver tissue lysate, Rat brain tissue lysate.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

JE56-93

RRID

AB_3071946

APPLICATION DILUTION

  • WB

  • 1:500-1:2,000

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 21 kDa.

Isotype

IgG

TARGET

UNIPROT #

O15431

PROTEIN NAME

SLC31A1

SYNONYMS

Copper transport 1 homolog antibody;Copper transporter 1 antibody;COPT1 antibody;COPT1_HUMAN antibody;CTR1 antibody;hCTR1 antibody;High affinity copper uptake protein 1 antibody;SLC31A1 antibody;solute carrier family 31 (copper tansporters) member 1 antibody;Solute carrier family 31 member 1 antibody

SUBCELLULAR LOCATION

Cell membrane.

FUNCTION

High affinity copper uptake protein 1 (Ctr1) is a protein that in humans is encoded by the SLC31A1 gene. Copper is an element essential for life, but excessive copper can be toxic or even lethal to the cell. Therefore, cells have developed sophisticated ways to maintain a critical copper balance, with the intake, export, and intracellular compartmentalization or buffering of copper strictly regulated. The 2 related genes ATP7A (MIM 300011) and ATP7B (MIM 606882), responsible for the human diseases Menkes syndrome (MIM 309400) and Wilson disease (MIM 277900), respectively, are involved in copper export. In S. cerevisiae, the copper uptake genes CTR1, CTR2, and CTR3 have been identified, and in human the CTR1 and CTR2 (MIM 603088) genes have been identified.

CITATIONS

  • A novel cuproptosis-related diagnostic gene signature and differential expression validation in atherosclerosis

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