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SPATA5L1 Rabbit Polyclonal Antibody (ER1901-68)

Price: Regular price $315.00

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Catalog# ER1901-68

Rabbit Polyclonal to SPATA5L1

Tested for

  • WB

  • IHC-P

Reacts with

  • Human

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Specifications

Product Type

Rabbit polyclonal primary

Product Name

SPATA5L1 Rabbit Polyclonal Antibody (ER1901-68)

Immunogen

Recombinant protein within human spata5l1 aa 379-580 / 753.

Host

Rabbit

Positive Control

K562 cell lysates, human liver tissue, Human small intestine tissue.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3069358

APPLICATION DILUTION

  • WB

  • 1:500-1:2000

  • IHC-P

  • 1:50-1:200

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

Predicted band size 80 kDa.

Isotype

IgG

TARGET

UNIPROT #

Q9BVQ7

PROTEIN NAME

SPATA5L1

SYNONYMS

FLJ12286 antibody;MGC5347 antibody;SPA5L_HUMAN antibody;SPATA5L1 antibody;Spermatogenesis-associated protein 5-like protein 1 antibody

SEQUENCE SIMILARITIES

Belongs to the AAA ATPase family. AFG2 subfamily.

SUBCELLULAR LOCATION

Cytoplasm

FUNCTION

Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly. Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface. Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility. Binds DNA, with a preference for supercoiled DNA and AT-rich DNA. Does not contribute to the internal structure of mitotic chromosomes. May play a role in chromatin organization.

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