UTF1 Mouse Monoclonal Antibody [E0-F4] (M1407-6)
Catalog# M1407-6
Mouse Monoclonal to UTF1
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WB
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IF-Cell
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Human
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Mouse
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Rat
Specifications
Product Type
Mouse monoclonal primary
Product Name
UTF1 Mouse Monoclonal Antibody [E0-F4] (M1407-6)
Immunogen
Synthetic peptide within human utf1 aa 51-100 / 341.
Host
Mouse
Positive Control
D3
Conjugation
Unconjugated
Clonality
Monoclonal
Clone Number
E0-F4
RRID
APPLICATION DILUTION
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WB
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1:500-1:1,000
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IF-Cell
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1:500-1:1,000
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2ug/ul
Purification
Protein A affinity purified.
Molecular Weight
36-50 kDa
Isotype
IgG2b
TARGET
UNIPROT #
PROTEIN NAME
UTF1
SYNONYMS
hUTF 1 antibody;hUTF1 antibody;Undifferentiated embryonic cell transcription factor 1 antibody;UTF 1 antibody;UTF1 antibody;UTF1_HUMAN antibody
POST-TRANSLATIONAL MODIFICATION
Phosphorylated.
SUBCELLULAR LOCATION
Nucleus
FUNCTION
Undifferentiated embryonic cell transcription factor 1 is a protein in humans that is encoded by the UTF1 gene. UTF1, first reported in 1998, is expressed in pluripotent cells including embryonic stem cells and embryonic carcinoma cells. Its expression is rapidly reduced upon differentiation. UTF1 protein is localized to the cell nucleus, where it functions to regulate the pluripotent chromatin state and buffer mRNA levels by promoting degradation of mRNA. Aberrant expression of UTF1 has also been reported in cervical cancer cells, where the UTF1 gene promoter loses methylation and becomes abnormally expressed compared to normal cervical cells.
CITATIONS
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Ying Zheng
Stimulated by retinoic acid gene 8 (Stra8) plays important roles in many stages of spermatogenesis
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IF
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mouse
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Citation
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