Rab9 Recombinant Rabbit Monoclonal Antibody [SR45-05] (ET1602-29)

UNIPROT #

P51151

PROTEIN NAME

Rab9

SYNONYMS

2410064E05Rik antibody;AI195561 antibody;DmRab9 antibody;Rab 9 antibody;RAB 9A antibody;RAB9 member RAS oncogene family antibody;RAB9A antibody;RAB9A member RAS oncogene family antibody;RAB9A_HUMAN antibody;RAS ASSOCIATED PROTEIN RAB9 antibody;Ras related protein Rab 9A antibody;Ras-related protein Rab-9A antibody;Sid6061p antibody;Sid99 antibody

SEQUENCE SIMILARITIES

Belongs to the small GTPase superfamily. Rab family.

SUBCELLULAR LOCATION

Cell membrane, Endoplasmic reticulum membrane, Golgi apparatus membrane.

FUNCTION

The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the SEC4 protein, which is 40% homologous to Rab proteins, is associated with secretory vesicles. At least eight members of the Rab subfamily have been identified, each of which is found at a particular stage of a membrane transport pathway.