Relaxin 3 receptor 1 Rabbit Polyclonal Antibody
Catalog# 0902-7
Relaxin 3 receptor 1 Rabbit Polyclonal Antibody
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WB
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IF-Cell
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IHC-P
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FC
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Mouse
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unconjugated
Overview
Product Name
Relaxin 3 receptor 1 Rabbit Polyclonal Antibody
Antibody Type
Rabbit Polyclonal Antibody
Immunogen
Synthetic peptide within Mouse Relaxin 3 receptor 1 aa 300-352.
Species Reactivity
Mouse
Validated Applications
WB, IF-Cell, IHC-P, FC
Molecular Weight
Predicted band size: 51kDa
Positive Control
Mouse brain,mouse spinal cord
Conjugation
unconjugated
RRID
Product Features
Form
Liquid
Concentration
Storage Instructions
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). Store at -20℃ long term.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Isotype
IgG
Purification Method
Immunogen affinity purified.
Application Dilution
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WB
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1:5,000~1:10,000
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IF-Cell
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1:100~1:200
Target
Function
Relaxin-3 receptor 1 belongs to the G-protein coupled receptor 1 family, It’s binding of the ligand inhibit cAMP accumulation. Upon ligand binding, the relaxin receptors activate adenylate cyclases through Gs proteins. RXFP3 is known to be important to several functions of the central nervous system, especially sensory processing under stressful conditions.
Background References
1. "Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein coupled receptor GPCR135."Liu C., Eriste E., Sutton S., Chen J., Roland B., Kuei C., Farmer N., Joernvall H., Sillard R., Lovenberg T.W.J. Biol. Chem. 278:50754-50764(2003)
2. "The novel G-protein coupled receptor SALPR shares sequence similarity with somatostatin and angiotensin receptors."Matsumoto M., Kamohara M., Sugimoto T., Hidaka K., Takasaki J., Saito T., Okada M., Yamaguchi T., Furuichi K.Gene 248:183-189(2000)
Sequence Similarity
Belongs to the G-protein coupled receptor 1 family.
Subcellular Location
Cell membrane
UNIPROT
Synonyms
G protein coupled receptor GPCR135 antibody
G protein coupled receptor SALPR antibody
G protein-coupled receptor SALPR antibody
G-protein coupled receptor GPCR135 antibody
GPCR 135 antibody
GPCR135 antibody
Gprotein coupled receptor SALPR antibody
Relaxin 3 receptor 1 antibody
Relaxin 3 receptor1 antibody
Relaxin 3/INSL7 receptor 1 antibody
ExpandImages
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Western blot analysis on mouse spinal cord (A) and mouse brain (B) using anti- Relaxin 3 receptor 1 polyclonal antibody.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"