CRY2 Mouse Monoclonal Antibody [Q3W3]
Catalog# EM2001-10
CRY2 Mouse Monoclonal Antibody [Q3W3]
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WB
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Human
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Mouse
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unconjugated
Overview
Product Name
CRY2 Mouse Monoclonal Antibody [Q3W3]
Antibody Type
Mouse Monoclonal Antibody
Immunogen
Recombinant human Cry2.
Species Reactivity
Human, Mouse
Validated Applications
WB
Molecular Weight
65 kDa
Conjugation
unconjugated
Clone Number
Q3W3
Product Features
Form
Liquid
Concentration
Storage Instructions
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Isotype
IgG1
Purification Method
Protein G affinity purified.
Application Dilution
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WB
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1:500-2000
Target
Function
This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene.
Background References
暂无
Subcellular Location
Cytoplasm. Nucleus. Translocated to the nucleus through interaction with other Clock proteins such as PER2 or ARNTL.
Images
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Sample:
Lane 1: HepG2 cell lysates
Lane 3: Human heart tissue lysates
Lane 3: Human liver tissue lysates
Lane 4: Mouse liver tissue lysates
Primary: Anti-CRY2 (EM2001-10) at 1/4000 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size: 65 kD
Observed band size: 60 kD
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"