Caspase-4 Rabbit Polyclonal Antibody
Catalog# ER62908
Caspase-4 Rabbit Polyclonal Antibody
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WB
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IHC-P
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Human
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unconjugated
Overview
Product Name
Caspase-4 Rabbit Polyclonal Antibody
Antibody Type
Rabbit Polyclonal Antibody
Immunogen
The antiserum was produced against synthesized peptide derived from human Caspase-4. AA range:75-124
Species Reactivity
Human
Validated Applications
WB, IHC-P
Molecular Weight
45 kDa
Positive Control
Placenta,Testis,Thymus,Uterus,
Conjugation
unconjugated
Product Features
Form
Liquid
Concentration
Storage Instructions
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Isotype
IgG
Purification Method
Immunogen affinity purified.
Application Dilution
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WB
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1:500-1:2000
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IHC-P
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1:100-1:300
Target
Function
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
Background References
暂无
UNIPROT
Synonyms
Apoptotic cysteine protease Mih1/TX antibody
CASP-4 antibody
CASP4 antibody
CASP4_HUMAN antibody
Caspase 4 apoptosis related cysteine peptidase antibody
Caspase-4 subunit 2 antibody
Caspase4 antibody
ICE(rel)-II antibody
ICE(rel)II antibody
ICEREL II antibody
ExpandImages
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Western blot analysis of lysates from 1) Hela ,2)THP-1, primary antibody was diluted at 1:1000, 4°over night, secondary antibody was diluted at 1:10000, 37° 1hour.
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Immunohistochemistry analysis of Caspase-4 antibody in paraffin-embedded human lung carcinoma tissue.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Alternative Products
Caspase-4 Mouse Monoclonal Antibody [A9G2]
Application: WB
Reactivity: Human,Cynomolgus monkey
Conjugate: unconjugated
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