Cyclin D2 Rabbit Polyclonal Antibody
Catalog# ER63155
Cyclin D2 Rabbit Polyclonal Antibody
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WB
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IHC-P
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Human
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Mouse
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Rat
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unconjugated
Overview
Product Name
Cyclin D2 Rabbit Polyclonal Antibody
Antibody Type
Rabbit Polyclonal Antibody
Immunogen
The antiserum was produced against synthesized peptide derived from human CCND2. AA range:240-289
Species Reactivity
Human, Mouse, Rat
Validated Applications
WB, IHC-P
Molecular Weight
42 kDa
Positive Control
Bone marrow,Heart,Placenta,Uterus,
Conjugation
unconjugated
Product Features
Form
Liquid
Concentration
Storage Instructions
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Isotype
IgG
Purification Method
Immunogen affinity purified.
Application Dilution
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WB
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1:500-1:2000
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IHC-P
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1:100-1:300
Target
Function
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK4 or CDK6 and functions as a regulatory subunit of the complex, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. Mutations in this gene are associated with megalencep
Background References
暂无
UNIPROT
Synonyms
CCND 2 antibody
ccnd2 antibody
CCND2_HUMAN antibody
CyclinD2 antibody
G1/S specific cyclin D2 antibody
G1/S-specific cyclin-D2 antibody
KIAK0002 antibody
MGC102758 antibody
MPPH3 antibody
Images
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Western blot analysis of lysates from 293 cells, using Cyclin D2 Antibody. The lane on the right is blocked with the synthesized peptide.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Citation
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Identification and Functional Validation of ACSL1 and FABP3 as Muscle-Related Genes Screened by Transcriptomics in Crossbred Duroc × Berkshire × Diannan Small-Eared Pigs
Journal: Genes
DOI: 10.3390/genes16050520
IF: 2.8
Application: WB
Reactivity: Mouse
Publish date: 2025 Apr
Alternative Products
Cyclin D2 Rabbit Polyclonal Antibody
Application: WB
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated
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