EAAT2 Rabbit Polyclonal Antibody
Catalog# ER60109
EAAT2 Rabbit Polyclonal Antibody
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WB
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Human
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Rat
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Mouse
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unconjugated
Overview
Product Name
EAAT2 Rabbit Polyclonal Antibody
Antibody Type
Rabbit Polyclonal Antibody
Immunogen
Synthetic Peptide of EAAT2
Species Reactivity
Human, Rat, Mouse
Validated Applications
WB
Molecular Weight
62 kDa
Positive Control
Brain,Brain cortex,Pancreas,
Conjugation
unconjugated
Product Features
Form
Liquid
Concentration
Storage Instructions
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Isotype
IgG
Purification Method
Immunogen affinity purified.
Application Dilution
-
WB
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1:1000-1:2000
Target
Function
This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified.
Background References
暂无
UNIPROT
Synonyms
EAA2_HUMAN antibody
EAAT2 antibody
Excitatory amino acid transporter 2 antibody
Excitotoxic amino acid transporter 2 antibody
Glial high affinity glutamate transporter antibody
GLT 1 antibody
GLT1 antibody
Glutamate aspartate transporter II antibody
Glutamate transporter 1 antibody
Glutamate/aspartate transporter II antibody
ExpandImages
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Western blot analysis of 1) Mouse Brain Tissue, 2)Rat Brain Tissue with EAAT2 Rabbit pAb diluted at 1:2,000.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Citation
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DL-3-n-butylphthalide inhibits astrocyte activation in the cortical penumbra of ischemia-reperfusion model rats via AKT signaling
Journal: Brain Research Bulletin
DOI: 10.1016/j.brainresbull.2025.111332
IF: 3.5
Application: WB
Reactivity: Rat
Publish date: 2025 Apr
Products with the same target and pathway
EAAT2 Recombinant Rabbit Monoclonal Antibody [PS01-62]
Application: WB,IHC-P,IHC-Fr
Reactivity: Mouse,Rat,Human
Conjugate: unconjugated
