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EDG-8 Rabbit Polyclonal Antibody

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Catalog# ER63318

EDG-8 Rabbit Polyclonal Antibody

Application

  • IHC-P

  • IF-Cell

Reactivity

  • Human

Conjugation

  • unconjugated

Overview

Product Name

EDG-8 Rabbit Polyclonal Antibody

Antibody Type

Rabbit Polyclonal Antibody

Immunogen

The antiserum was produced against synthesized peptide derived from human EDG8. AA range:335-384

Species Reactivity

Human

Validated Applications

IHC-P, IF-Cell

Positive Control

Lymphocyte,Mammary gland,Skin,

Conjugation

unconjugated

Product Features

Form

Liquid

Concentration

Storage Instructions

Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.

Storage Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Isotype

IgG

Purification Method

Immunogen affinity purified.

Application Dilution

  • IHC-P

  • 1:100-1:300

  • IF-cell

  • 1:100-1:500

Target

Function

The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e. g. EDG1; MIM 601974) are S1P receptors; others (e. g. EDG2; MIM 602282) are LPA receptors.,

Background References

暂无

UNIPROT

SwissProt: Q9H228 Human

Synonyms

EDG 8 antibody

EDG8 S1P receptor antibody

Endothelial differentiation G protein coupled receptor 8 antibody

Endothelial differentiation G-protein-coupled receptor 8 antibody

Endothelial Differentiation Gene 8 antibody

Endothelial differentiation sphingolipid G protein coupled receptor 8 antibody

S1P receptor 5 antibody

S1P receptor Edg 8 antibody

S1P receptor Edg-8 antibody

S1P receptor Edg8 antibody

Expand

Images

  • Immunofluorescence analysis of A549 cells, using EDG8 Antibody. The picture on the right is blocked with the synthesized peptide.

    Immunofluorescence analysis of A549 cells, using EDG8 Antibody. The picture on the right is blocked with the synthesized peptide.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"