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GCN5 Rabbit Polyclonal Antibody

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Catalog# ER63516

GCN5 Rabbit Polyclonal Antibody

Application

  • WB

  • IHC-P

Reactivity

  • Human

  • Mouse

Conjugation

  • unconjugated

This product has been cited in peer reviewed publications, see list HERE

Overview

Product Name

GCN5 Rabbit Polyclonal Antibody

Antibody Type

Rabbit Polyclonal Antibody

Immunogen

The antiserum was produced against synthesized peptide derived from human GCN5L2. AA range:691-740

Species Reactivity

Human, Mouse

Validated Applications

WB, IHC-P

Molecular Weight

Predicted band size: 94 kDa

Conjugation

unconjugated

Product Features

Form

Liquid

Concentration

Storage Instructions

Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.

Storage Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Isotype

IgG

Purification Method

Immunogen affinity purified.

Application Dilution

  • WB

  • 1:500-1:2000

  • IHC-P

  • 1:100-1:300

Target

Function

KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al. 2009

Background References

暂无

UNIPROT

SwissProt: Q92830 Human

Synonyms

1110051E14Rik antibody

AW212720 antibody

EC 2.3.1.48 antibody

GCN 5 antibody

GCN5 (general control of amino-acid synthesis

yeast

homolog)-like 2 antibody

Gcn5 antibody

GCN5 general control of amino-acid synthesis 5-like 2 (yeast) antibody

GCN5L2 antibody

Expand

Images

  • Western Blot analysis of various cells using GCN5 Polyclonal Antibody diluted at 1:1,000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).

    Western Blot analysis of various cells using GCN5 Polyclonal Antibody diluted at 1:1,000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).

  • Western Blot analysis of Hela cells using GCN5 Polyclonal Antibody diluted at 1:1,000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).

    Western Blot analysis of Hela cells using GCN5 Polyclonal Antibody diluted at 1:1,000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).

  • Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.

    Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.

  • Western blot analysis of lysates from mouse brain, using GCN5L2 Antibody. The lane on the right is blocked with the synthesized peptide.

    Western blot analysis of lysates from mouse brain, using GCN5L2 Antibody. The lane on the right is blocked with the synthesized peptide.

  • Western blot analysis of the lysates from RAW264.7cells using GCN5L2 antibody.

    Western blot analysis of the lysates from RAW264.7cells using GCN5L2 antibody.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Citation