FKBP38 Rabbit Polyclonal Antibody
Catalog# ER1908-88
FKBP38 Rabbit Polyclonal Antibody
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WB
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Mouse
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Rat
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unconjugated
Overview
Product Name
FKBP38 Rabbit Polyclonal Antibody
Antibody Type
Rabbit Polyclonal Antibody
Immunogen
KLH conjugated synthetic peptide derived from human FKBP38 255-350/412
Species Reactivity
Mouse, Rat
Validated Applications
WB
Molecular Weight
46 KDa
Positive Control
Widely expressed. Highest levels seen in the brain.
Conjugation
unconjugated
Product Features
Form
Liquid
Concentration
Storage Instructions
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage Buffer
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Isotype
IgG
Purification Method
Protein A affinity purified.
Application Dilution
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WB
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1:500-2000
Target
Function
Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.
Background References
暂无
Subcellular Location
Mitochondrion membrane; Single-pass membrane protein; Cytoplasmic side (By similarity).
UNIPROT
Synonyms
38 kDa FK506-binding protein antibody
38 kDa FKBP antibody
38kDa antibody
FK506 binding protein 8 antibody
FK506 binding protein 8
38kDa antibody
FK506 binding protein
38kDa antibody
FK506-binding protein 8 antibody
FKBP 38 antibody
ExpandImages
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Sample:
Cerebrum (Mouse) Lysate at 40 ug
Primary: Anti- FKBP38 (ER1908-88) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 46 kD
Observed band size: 46 kD
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Alternative Products
FKBP38 Recombinant Rabbit Monoclonal Antibody [JE40-31]
Application: WB,IF-Cell,IHC-P,FC
Reactivity: Human
Conjugate: unconjugated
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