GADD45B Rabbit Polyclonal Antibody
Catalog# ER61480
GADD45B Rabbit Polyclonal Antibody
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WB
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Human
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Mouse
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unconjugated
Overview
Product Name
GADD45B Rabbit Polyclonal Antibody
Antibody Type
Rabbit Polyclonal Antibody
Immunogen
Synthesized peptide derived from human protein . at AA range: 90-170
Species Reactivity
Human, Mouse
Validated Applications
WB
Molecular Weight
17 kDa
Positive Control
Brain,Colon carcinoma,Lung carcinoma,
Conjugation
unconjugated
Product Features
Form
Liquid
Concentration
Storage Instructions
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Isotype
IgG
Purification Method
Immunogen affinity purified.
Application Dilution
-
WB
-
1:500-1:2000
Target
Function
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.
Background References
暂无
UNIPROT
Synonyms
GA45B_HUMAN antibody
GADD45 Beta antibody
Gadd45b antibody
GADD45BETA antibody
Growth arrest and DNA damage inducible 45 beta antibody
Growth arrest and DNA damage inducible beta antibody
Growth arrest and DNA damage-inducible gene GADD45
beta antibody
Growth arrest and DNA damage-inducible protein GADD45 beta antibody
Growth arrest and DNA-damage-inducible protein GADD45 beta antibody
ExpandImages
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Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°over night.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Alternative Products
GADD45B Recombinant Rabbit Monoclonal Antibody [PSH09-52]
Application: WB
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated
Products with the same target and pathway