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Rat IL-4, C-His, Flag Tag Protein

Usd: 159

Specification

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Catalog# HA210759

Rat IL-4, C-His, Flag Tag Protein

Product Information

Product name

Rat IL-4, C-His, Flag Tag Protein

Catalog No.

HA210759

Predicted molecular mass

15.1 kD

Protein construction description

A DNA sequence encoding the rat IL-4 protein (P20096) (Cys 25-Ser 147) was expressed with both His, Flag tag at the C-terminus.

Accession

P20096

Protein construction

IL-4 (25-147) His Flag

Source

HEK293

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Rat

Background

Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.

Usage guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.