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Mouse IL-7, Tag Free Protein

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Usd: 379

Specification

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Catalog# HA211019

Mouse IL-7, Tag Free Protein

Product Information

Product name

Mouse IL-7, Tag Free Protein

Catalog No.

HA211019

Predicted molecular mass

15.3 kD

Protein construction description

A DNA sequence encoding the mouse IL-7 protein (P10168) (Glu 26-Ile 154) was expressed with tag free.

Accession

P10168

Protein construction

IL-7 (26-154)

Source

HEK293

Bio Activity

Measured in a cell proliferation assay using mouse splenocytes pre-stimulated with 0.3 μg/mL anti-CD3 for 24 hours. The ED50 for this effect is 0.07-0.3 ng/mL.

Purity

>95% as determined by SDS-PAGE.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Mouse

Background

Interleukin 7 (IL-7) is a protein that in humans is encoded by the IL7 gene. IL-7 is a hematopoietic growth factor secreted by stromal cells in the bone marrow and thymus. It is also produced by keratinocytes, dendritic cells, hepatocytes, neurons, and epithelial cells, but is not produced by normal lymphocytes. A study also demonstrated how the autocrine production of the IL-7 cytokine mediated by T-cell acute lymphoblastic leukemia (T-ALL) can be involved in the oncogenic development of T-ALL and offer novel insights into T-ALL spreading.

Usage guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.