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Mouse ICAM-1/CD54, C-His Tag (ECD) Protein

Usd: 379

Specification

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Catalog# HA211066

Mouse ICAM-1/CD54, C-His Tag (ECD) Protein

Product Information

Product name

Mouse ICAM-1/CD54, C-His Tag (ECD) Protein

Catalog No.

HA211066

Predicted molecular mass

52 kD

Protein construction description

A DNA sequence encoding the mouse ICAM-1/CD54 protein (P13597) (Gln 24-Asn 485) was expressed with a His tag at the C-terminus.

Accession

P13597

Protein construction

ICAM-1/CD54 (24-485) His

Source

HEK293

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Mouse

Background

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. Expressed at low level on a subpopulation of lymphocytes, macrophages, and endothelial cells, but is strongly induced on these cells, and on fibroblasts and epithelial cells.

Usage guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.