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Human Chitotriosidase/CHIT1, C-His Tag Protein

Usd: 140

Specification

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Catalog# HA211215

Human Chitotriosidase/CHIT1, C-His Tag Protein

Product Information

Product name

Human Chitotriosidase/CHIT1, C-His Tag Protein

Catalog No.

HA211215

Predicted molecular mass

51.2 kD

Protein construction description

A DNA sequence encoding the human Chitotriosidase/CHIT1 (Q13231-1) (Ala 22-Asn 466) was expressed with a His tag at the C-terminus.

Accession

Q13231-1

Protein construction

Chitotriosidase/CHIT1 (22-466) His

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity. Very high plasma levels of CHIT1 are found in patients with Gaucher disease type 1 (GD I). Can be used as diagnostic aid and to evaluate the success of treatment that brings levels back to normal.

Usage guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.