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Mouse CREB1, C-His Tag Protein

Usd: 129

Specification

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Catalog# HA211601

Mouse CREB1, C-His Tag Protein

Product Information

Product name

Mouse CREB1, C-His Tag Protein

Catalog No.

HA211601

Predicted molecular mass

29 kD

Protein construction description

A DNA sequence encoding the mouse CREB1 protein (Q01147-2) (Met 1 -Ala 259) was expressed with a His tag at the C-terminus.

Accession

Q01147-2

Protein construction

CREB1 (1-259) His

Source

E.coli

Bio Activity

Testing in progress.

Purity

>90% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Mouse

Background

CAMP responsive element binding protein 1, also known as CREB-1. This protein binds the cAMP response element, a DNA nucleotide sequence present in many viral and cellular promoters. The binding of CREB1 stimulates transcription. This protein is a CREB transcription factor that is a member of the leucine zipper family of DNA-binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.

Usage guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.