VGLUT1 Recombinant Antibody [PSH10-53] - Chicken IgY (Chimeric) - BSA and Azide free
Catalog# HA610312
VGLUT1 Recombinant Antibody [PSH10-53] - Chicken IgY (Chimeric) - BSA and Azide free
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IHC-Fr
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Mouse
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unconjugated
Overview
Product Name
VGLUT1 Recombinant Antibody [PSH10-53] - Chicken IgY (Chimeric) - BSA and Azide free
Antibody Type
Recombinant Chimeric Antibody
Immunogen
Recombinant protein within Mouse VGLUT1 aa 1-560.
Species Reactivity
Mouse
Validated Applications
IHC-Fr
Target Molecular Weight
Predicted band size: 62 kDa
Conjugation
unconjugated
Clone Number
PSH10-53
Product Features
Form
Liquid
Concentration
1mg/ml
Storage Instructions
Store at 2-8℃. Avoid freeze.
Storage Buffer
1*PBS (pH7.4).
Isotype
IgY
Purification Method
Protein A affinity purified.
Application Dilution
Target
Function
Vesicular glutamate transporter 1 (VGLUT1) is a protein that in humans is encoded by the SLC17A7 gene. The protein encoded by this gene is a vesicle-bound, sodium-dependent phosphate transporter that is specifically expressed in the neuron-rich regions of the brain. It is preferentially associated with the membranes of synaptic vesicles and functions in glutamate transport. The protein shares 82% identity with the differentiation-associated Na-dependent inorganic phosphate cotransporter and they appear to form a distinct class within the Na+/Pi cotransporter family.
Background References
1. Souter EA et al. Disruption of VGLUT1 in Cholinergic Medial Habenula Projections Increases Nicotine Self-Administration. eNeuro. 2022 Jan
2. Jin S et al. Molecular Profiling of VGluT1 AND VGluT2 Ventral Subiculum to Nucleus Accumbens Shell Projections. Neurochem Res. 2023 Aug
Subcellular Location
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane, Cell membrane, Synapse, synaptosome.
UNIPROT
Synonyms
BNPI antibody
Brain specific Na (+) dependent inorganic phosphate cotransporter antibody
Brain specific Na dependent inorganic phosphate cotransporter antibody
Brain-specific Na(+)-dependent inorganic phosphate cotransporter antibody
Slc17a7 antibody
Solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 antibody
Solute carrier family 17 member 7 antibody
Vesicular glutamate transporter 1 antibody
VGLU1_HUMAN antibody
VGLUT 1 antibody
ExpandImages
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This data was developed using HA601478, the same antibody clone in a different buffer formulation.
Application: IHC-Fr
Species: Mouse
Site: cerebral cortex
Sample: Frozen section
Antibody concentration: 1/200
Antigen retrieval: Not required
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"