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TPH2 Recombinant Antibody [PSH04-89] - Guinea pig IgG2 (Chimeric) - BSA and Azide free (HA610322)

Price: Regular price $649.00

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Catalog# HA610322

to TPH2

Tested for

  • IHC-Fr

  • WB

Reacts with

  • Mouse

  • Rat

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

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Specifications

Product Type

Recombinant Chimeric Antibody primary

Product Name

TPH2 Recombinant Antibody [PSH04-89] - Guinea pig IgG2 (Chimeric) - BSA and Azide free (HA610322)

Immunogen

Recombinant protein with human thp2 aa 1-490.

Positive Control

Mouse brain tissue lysate, Rat brain tissue lysate.

Conjugation

Unconjugated

Clone Number

PSH04-89

APPLICATION DILUTION

  • IHC-Fr

  • 1:200-1:500

  • WB

  • 1:5,000

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4).

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 56 kDa

TARGET

UNIPROT #

Q8CGV2

PROTEIN NAME

TPH2

SYNONYMS

MGC138871 antibody;ADHD7 antibody;FLJ37295 antibody;MGC138872 antibody;Neuronal tryptophan hydroxylase antibody;NTPH antibody;TPH 2 antibody;Tph2 antibody;TPH2_HUMAN antibody;Tryptophan 5-hydroxylase 2 antibody;Tryptophan 5-monooxygenase 2 antibody;Tryptophan hydroxylase 2 antibody

SUBCELLULAR LOCATION

Cytosol, neuron projection.

FUNCTION

Tryptophan hydroxylase 2 (TPH2) is an isozyme of tryptophan hydroxylase found in vertebrates. In humans, TPH2 is primarily expressed in the serotonergic neurons of the brain, with the highest expression in the raphe nucleus of the midbrain. Until the discovery of TPH2 in 2003, serotonin levels in the central nervous system were believed to be regulated by serotonin synthesis in peripheral tissues, in which tryptophan hydroxylase is the dominant form.

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