TAZ / WWTR1 Recombinant Rabbit Monoclonal Antibody - BSA and Azide free [PSH15-57] (HA751568)

UNIPROT #

Q9GZV5

PROTEIN NAME

TAZ / WWTR1

SYNONYMS

DKFZP586I1419 antibody;FLJ27004 antibody;FLJ45718 antibody;OTTHUMP00000215994 antibody;OTTHUMP00000215995 antibody;OTTHUMP00000215996 antibody;OTTHUMP00000216001 antibody;TAZ antibody;Transcriptional co activator with PDZ binding motif antibody;Transcriptional coactivator with PDZ binding motif antibody;Transcriptional coactivator with PDZ-binding motif antibody;WW domain containing transcription regulator 1 antibody;WW domain containing transcription regulator protein 1 antibody;WW domain-containing transcription regulator protein 1 antibody;WWTR 1 antibody;WWTR1 antibody;WWTR1_HUMAN antibody

SUBCELLULAR LOCATION

Nucleus, Cytoplasm, Cell membrane, Cell junction, tight junction.

FUNCTION

WW domain-containing transcription regulator protein 1 (WWTR1), also known as Transcriptional coactivator with PDZ-binding motif (TAZ), is a protein that in humans is encoded by the WWTR1 gene. WWTR1 acts as a transcriptional coregulator and has no effect on transcription alone. When in complex with transcription factor binding partners, WWTR1 helps promote gene expression in pathways associated with development, cell growth and survival, and inhibiting apoptosis. Aberrant WWTR1 function has been implicated for its role in driving cancers. WWTR1 is often referred to as TAZ due to its initial characterization with the name TAZ. However, WWTR1 (TAZ) is not to be confused with the protein tafazzin, which originally held the official gene symbol TAZ, and is now TAFAZZIN.