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HDAC5 Rabbit Polyclonal Antibody

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Catalog# ER64245

HDAC5 Rabbit Polyclonal Antibody

Application

  • WB

  • IHC-P

  • IF-Cell

Reactivity

  • Human

  • Mouse

  • Rat

Conjugation

  • unconjugated

This product has been cited in peer reviewed publications, see list HERE

Overview

Product Name

HDAC5 Rabbit Polyclonal Antibody

Antibody Type

Rabbit Polyclonal Antibody

Immunogen

The antiserum was produced against synthesized peptide derived from human HDAC5. AA range:1073-1122

Species Reactivity

Human, Mouse, Rat

Validated Applications

WB, IHC-P, IF-Cell

Molecular Weight

121 kDa

Positive Control

Brain,Colon carcinoma,Eye,Ovary,Testis,

Conjugation

unconjugated

RRID

AB_3083653

Product Features

Form

Liquid

Concentration

Storage Instructions

Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.

Storage Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Isotype

IgG

Purification Method

Immunogen affinity purified.

Application Dilution

  • WB

  • 1:500-1:2000

  • IHC-P

  • 1:100-1:300

  • IF-cell

  • 1:100-1:500

Target

Function

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.

Background References

暂无

UNIPROT

SwissProt: Q9UQL6 Human

Synonyms

Antigen NY CO 9 antibody

Antigen NY-CO-9 antibody

HD5 antibody

HDAC 5 antibody

HDAC5 antibody

HDAC5_HUMAN antibody

Histone deacetylase 5 antibody

NY CO 9 antibody

Images

  • Western Blot analysis of 3T3 and K562 cells using NY-CO-9 Polyclonal Antibody

    Western Blot analysis of 3T3 and K562 cells using NY-CO-9 Polyclonal Antibody

  • Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4°,overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.

    Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4°,overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Citation

Alternative Products

metafield image

HDAC5 Recombinant Rabbit Monoclonal Antibody [PSH08-70]

Application: WB,IHC-P,IF-Cell,IP,ChIP

Reactivity: Human,Mouse,Rat

Conjugate: unconjugated

Products with the same target and pathway

metafield image

HDAC5 Recombinant Rabbit Monoclonal Antibody [PSH08-70]

Application: WB,IHC-P,IF-Cell,IP,ChIP

Reactivity: Human,Mouse,Rat

Conjugate: unconjugated