HSP70 (Acetyl K246) Rabbit Polyclonal Antibody
Catalog# ER60056
HSP70 (Acetyl K246) Rabbit Polyclonal Antibody
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WB
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Human
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unconjugated
Overview
Product Name
HSP70 (Acetyl K246) Rabbit Polyclonal Antibody
Antibody Type
Rabbit Polyclonal Antibody
Immunogen
Synthesized acetyl-peptide derived from the Internal region of human HSP70 around the acetylation site of K246.
Species Reactivity
Human
Validated Applications
WB
Molecular Weight
70 kDa
Positive Control
Brain,Cajal-Retzius cell,Embryonic kidney,Epithelium,Fetal
Conjugation
unconjugated
Product Features
Form
Liquid
Concentration
Storage Instructions
-15℃ to -25℃/1 year(Do not lower than -25℃)
Storage Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Isotype
IgG
Purification Method
Immunogen affinity purified.
Application Dilution
-
WB
-
1:500-1:2000
Target
Function
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.
Background References
暂无
Subcellular Location
Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Secreted . Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Synonyms
HSPA1A antibody
HSPA1 antibody
HSPA1B antibody
Heat shock 70 kDa protein 1A/1B antibody
Heat shock 70 kDa protein 1/2 antibody
HSP70-1/HSP70-2 antibody
HSP70.1/HSP70.2 antibody
Images
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Western Blot analysis of RAT-kidney cells using Acetyl-HSP70 (K246) Polyclonal Antibody diluted at 1:1,000. Secondary antibody was diluted at 1:20,000
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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