PE Conjugated Human NCAM1 / CD56 Recombinant Rabbit Monoclonal Antibody [PSH06-53]
Catalog# HA720215F
PE Conjugated Human NCAM1 / CD56 Recombinant Rabbit Monoclonal Antibody [PSH06-53]
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FC
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Human
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PE
Overview
Product Name
PE Conjugated Human NCAM1 / CD56 Recombinant Rabbit Monoclonal Antibody [PSH06-53]
Antibody Type
Recombinant Rabbit monoclonal Antibody
Immunogen
Recombinant protein within human NCAM1 / CD56 aa 20-718 (Extracellular).
Species Reactivity
Human
Validated Applications
FC
Molecular Weight
Predicted band size: 95 kDa
Positive Control
Human peripheral blood lymphocytes.
Conjugation
PE
Clone Number
PSH06-53
Product Features
Form
Liquid
Concentration
1 mg/mL.(The concentration of this product may be batch-dependent)
Storage Instructions
Store at 2℃ to 8℃. Avoid repeated freeze / thaw cycles.
Storage Buffer
Supplied in phosphate-buffered solution, pH 7.2, containing 0.2% ProClean 950 and BSA.
Isotype
IgG
Purification Method
Protein A affinity purified.
Application Dilution
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FC
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5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Target
Function
Neural cell adhesion molecule (NCAM), also called CD56, is a homophilic binding glycoprotein expressed on the surface of neurons, glia and skeletal muscle. Although CD56 is often considered a marker of neural lineage commitment due to its discovery site, CD56 expression is also found in, among others, the hematopoietic system. Here, the expression of CD56 is mostly associated with, but not limited to, natural killer cells. CD56 has been detected on other lymphoid cells, including gamma delta (γδ) Τ cells and activated CD8+ T cells, as well as on dendritic cells. NCAM has been implicated as having a role in cell–cell adhesion, neurite outgrowth, synaptic plasticity, and learning and memory.
Background References
1. Cocker ATH et al. The CD56-CD16+ NK cell subset in chronic infections. Biochem Soc Trans. 2023 Jun
Subcellular Location
Cell membrane.
UNIPROT
Synonyms
antigen MSK39 identified by monoclonal antibody 5.1H11 antibody
antigen recognized by monoclonal antibody 5.1H11 antibody
CD56 antibody
cell adhesion molecule, neural, 1 antibody
MSK 39 antibody
MSK39 antibody
N-CAM-1 antibody
NCAM 1 antibody
NCAM antibody
NCAM C antibody
ExpandImages
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Flow cytometric analysis of human peripheral blood lymphocytes labelling Human NCAM1 / CD56 (HA720215F, PE) and CD3 (HA600118F, APC).
Cells were washed twice with cold PBS and resuspend. Then incubated for 1 hour at +4℃ with Human NCAM1 / CD56 (HA720215F, PE, 1/1,000) compared with Rabbit IgG Isotype Control (PE, 1/1,000).
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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