Biotin Conjugated Human Prolactin Recombinant Rabbit Monoclonal Antibody [PSH03-14] - Detector
Overview
Product Name
Biotin Conjugated Human Prolactin Recombinant Rabbit Monoclonal Antibody [PSH03-14] - Detector
Antibody Type
Recombinant Rabbit monoclonal Antibody
Immunogen
Recombinant protein within human Prolactin aa 29-227.
Species Reactivity
Human, Cynomolgus monkey
Validated Applications
ELISA(Det)
Molecular Weight
Predicted band size: 25.9 kDa
Positive Control
Recombinant standard Human Prolactin (HA210676).
Conjugation
Biotin
Clone Number
PSH03-14
Product Features
Form
Liquid
Concentration
1 mg/ml(The concentration of this product may be batch-dependent)
Storage Instructions
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). Store at -20℃ long term.
Storage Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% ProClin300.
Isotype
IgG
Purification Method
Protein A affinity purified.
Application Dilution
-
ELISA(Det)
-
Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH03-13] to Human Prolactin (Capture) (HA721941) and recombinant standard Human Prolactin (HA210676) as the standard. The reference range value is 61.73-5,000 pg/mL.
Target
Function
Prolactin (PRL), also known as lactotropin and mammotropin, is a protein best known for its role in enabling mammals to produce milk. It is influential in over 300 separate processes in various vertebrates, including humans. Prolactin is secreted from the pituitary gland in response to eating, mating, estrogen treatment, ovulation and nursing. It is secreted heavily in pulses in between these events. Prolactin plays an essential role in metabolism, regulation of the immune system and pancreatic development. Prolactin has a wide variety of effects. It stimulates the mammary glands to produce milk (lactation): increased serum concentrations of prolactin during pregnancy cause enlargement of the mammary glands and prepare for milk production, which normally starts when levels of progesterone fall by the end of pregnancy and a suckling stimulus is present. Prolactin plays an important role in maternal behavior.
Background References
1. Schuler LA et al. Prolactin: The Third Hormone in Breast Cancer. Front Endocrinol (Lausanne). 2022 Jun
2. Szewczyk AK et al. Prolactin and oxytocin: potential targets for migraine treatment. J Headache Pain. 2023 Mar
Subcellular Location
Secreted
UNIPROT
Synonyms
Decidual prolactin
GHA1
Growth hormone A1
Lactogenic hormone
Luteotropic hormone
Mammotropin
PRL
Prolactin
Prolactin precursor
Images
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Products with the same target and pathway
Human Prolactin Recombinant Rabbit Monoclonal Antibody [PSH03-14] - BSA and Azide free (Detector)
Application: ELISA(Det)
Reactivity: Human,Cynomolgus monkey
Conjugate: unconjugated
