Iba1 Rabbit Polyclonal Antibody
Catalog# ER1802-20
Iba1 Rabbit Polyclonal Antibody
-
IHC-P
-
Human
-
Mouse
-
unconjugated
Overview
Product Name
Iba1 Rabbit Polyclonal Antibody
Antibody Type
Rabbit Polyclonal Antibody
Immunogen
Synthetic peptide within C-terminal human Iba1.
Species Reactivity
Human, Mouse
Validated Applications
IHC-P
Molecular Weight
17/10/15 kDa
Positive Control
Human tonsil tissue, human spleen tissue, mouse spleen tissue.
Conjugation
unconjugated
RRID
Product Features
Form
Liquid
Concentration
Storage Instructions
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Isotype
IgG
Purification Method
Immunogen affinity purified.
Application Dilution
-
IHC-P
-
1:50-1:200
Target
Function
Ionized calcium-binding adapter molecule 1 (Iba1), also known as allograft inflammatory factor-1 (AIF-1), is a 147 amino acid cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. Iba1, containing two EF domains, is induced by cytokines and interferons. In an unstimulated state, Iba1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding Iba1 maps to chromosome 6p21.33 and resides in the tumor necrosis factor (TNF) cluster of genes located in the region represented by the human major histocompatibility complex (MHC).
Background References
暂无
Tissue Specificity
Detected in T-lymphocytes and peripheral blood mononuclear cells.
Post-translational Modification
Phosphorylated on serine residues.
Subcellular Location
Plasma membrane. Cytoskeleton.
Synonyms
AIF 1 antibody
AIF-1 antibody
Aif1 antibody
AIF1 protein antibody
AIF1_HUMAN antibody
Allograft inflammatory factor 1 antibody
Allograft inflammatory factor 1 splice variant G antibody
allograft inflammatory factor-1 splice variant Hara-1 antibody
balloon angioplasty responsive transcription antibody
BART 1 antibody
ExpandImages
-
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Iba1 antibody. Counter stained with hematoxylin.
-
Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-Iba1 antibody. Counter stained with hematoxylin.
-
Immunohistochemical analysis of paraffin-embedded mouse spleen tissue using anti-Iba1 antibody. Counter stained with hematoxylin.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Citation
-
Effect of Puerarin on Chronic Alcoholic Encephalopathy by Modulating the “Microbiota-Gut-Brain Axis” Lipopolysaccharides/Toll-Like Receptors 4/Nuclear Factor Kappa-B Inflammatory Pathway
Journal: Phytotherapy Research
DOI: 10.1002/ptr.70197
IF: 6.3
Application: IHC
Reactivity: Mouse
Publish date: 2026 Jan
-
Fluorescence spectra of cell markers in the spinal cord for a murine model of amyotrophic lateral sclerosis with heat shock protein overexpression
Journal: Laser Physics Letters
DOI: 10.1088/1612-202X/ada7d8
IF: 1.4
Application: IF-tissue
Reactivity: Mouse
Publish date: 2025 Jun
-
Porphyromonas gingivalis Induces Disturbance of Kynurenine Metabolism Through the Gut-Brain Axis: Implications for Alzheimer’s Disease
Journal: JOURNAL OF DENTAL RESEARCH
DOI: 10.1177/00220345241303141
IF: 5.9
Application: IHC
Reactivity: Mouse
Publish date: 2025 Feb
-
Quantitative Immunofluorescence Mapping of HSP70’s Neuroprotective Effects in FUS-ALS Mouse Models
Journal: Applied Sciences-Basel
DOI: 10.3390/app142411614
IF: 2.5
Application: IF-tissue
Reactivity: Mouse
Publish date: 2024 Dec
Alternative Products
Iba1 Recombinant Rabbit Monoclonal Antibody [JM36-62]
Application: WB,IHC-P,IHC-Fr,IF-Tissue,IF-Cell,FC,IP,mIHC
Reactivity: Human,Mouse,Rat,Pig,Cynomolgus monkey
Conjugate: unconjugated
Products with the same target and pathway
Iba1 Recombinant Mouse Monoclonal Antibody [8G8] - BSA and Azide free
Application: WB,IHC-P,FC,IP,IHC-Fr,IF-Cell,IF-Tissue
Reactivity: Human,Mouse,Rat,Cynomolgus monkey,Pig
Conjugate: unconjugated
Iba1 Recombinant Rabbit Monoclonal Antibody [JM36-62]
Application: WB,IHC-P,IHC-Fr,IF-Tissue,IF-Cell,FC,IP,mIHC
Reactivity: Human,Mouse,Rat,Pig,Cynomolgus monkey
Conjugate: unconjugated
Iba1 Recombinant Antibody [JM36-62] - Chicken IgY (Chimeric) - BSA and Azide free
Application: IHC-Fr,WB,IF-Cell,FC
Reactivity: Human,Mouse,Rat,Pig,Cynomolgus monkey
Conjugate: unconjugated
iFluor™ 488 Conjugated Iba1 Recombinant Rabbit Monoclonal Antibody [JM36-62]
Application: IF-Cell,FC
Reactivity: Human,Mouse,Rat
Conjugate: iFluor™ 488
Iba1 Recombinant Rabbit Monoclonal Antibody [JM36-62] - BSA and Azide free
Application: WB,IHC-P,IHC-Fr,IF-Tissue,IF-Cell,FC,IP
Reactivity: Human,Mouse,Rat,Pig,Cynomolgus monkey
Conjugate: unconjugated
Iba1 Recombinant Antibody [JM36-62] - Rat IgG1 (Chimeric) - BSA and Azide free
Application: IHC-Fr,IHC-P,IF-Cell
Reactivity: Mouse,Rat,Cynomolgus monkey,Pig
Conjugate: unconjugated
Iba1 Recombinant Antibody [JM36-62] - Guinea pig IgG2 (Chimeric) - BSA and Azide free
Application: IHC-Fr,WB
Reactivity: Human,Mouse,Rat,Cynomolgus monkey,Pig
Conjugate: unconjugated
Iba1 Recombinant Mouse Monoclonal Antibody [8G8]
Application: WB,IHC-P,FC,IP,IHC-Fr,IF-Cell,IF-Tissue
Reactivity: Human,Mouse,Rat,Cynomolgus monkey,Pig
Conjugate: unconjugated
Iba1 Recombinant Antibody [JM36-62] - Rat IgG1 (Chimeric)
Application: IHC-Fr,IHC-P,mIHC,IF-Cell
Reactivity: Mouse,Rat,Cynomolgus monkey,Pig
Conjugate: unconjugated
Iba1 Recombinant Antibody [JM36-62] - Guinea pig IgG2 (Chimeric)
Application: IHC-Fr,WB
Reactivity: Human,Mouse,Rat,Cynomolgus monkey,Pig
Conjugate: unconjugated
