Integrin alpha 1 Recombinant Rabbit Monoclonal Antibody [PSH14-04]
Catalog# HA723594
Integrin alpha 1 Recombinant Rabbit Monoclonal Antibody [PSH14-04]
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FC
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Human
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unconjugated
Overview
Product Name
Integrin alpha 1 Recombinant Rabbit Monoclonal Antibody [PSH14-04]
Antibody Type
Recombinant Rabbit monoclonal Antibody
Immunogen
Recombinant protein within human Integrin alpha 1 aa 630-1,141.
Species Reactivity
Human
Validated Applications
FC
Target Molecular Weight
Predicted band size: 131 kDa
Positive Control
HeLa.
Conjugation
unconjugated
Clone Number
PSH14-04
Reactivity Data
Verified (internally validated)
Reported in literature (not internally validated)
Predicted reactive (based on sequence homology)
Not recommended (failed internal validation)
| WB | IHC-P | FC | IF-Cell | |
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| human |
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| mouse |
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| rat |
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Product Features
Form
Liquid
Concentration
1 mg/mL.(The concentration of this product may be batch-dependent)
Storage Instructions
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). Store at -20℃ long term.
Storage Buffer
1*PBS (pH7.4), 0.1% BSA, 40% Glycerol, 0.2% Proclean 950.
Isotype
IgG
Purification Method
Protein A affinity purified.
Application Dilution
-
FC
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1:1,000
Target
Function
Integrin alpha-1 also CD49a is an integrin alpha subunit encoded in humans by the gene ITGA1. It makes up half of the α1β1 integrin duplex. Though CD49a can bind a number of ligands including collagen IV, collagen I, and others. CD49a has been implicated as a marker of tissue resident memory T cells, where it may be coexpressed with other markers CD103 and CD69. It has been shown to affect the motility of T cells.
Background References
1. Bayer ML et al. Influence of the integrin alpha-1 subunit and its relationship with high-fat diet upon extracellular matrix synthesis in skeletal muscle and tendon. Cell Tissue Res. 2020 Jul
2. Ren Y et al. ITGA1 Promotes Glioma Cell Proliferation and Affects Immune Cell Infiltration in Low-Grade Glioma. Mediators Inflamm. 2024 Oct
Subcellular Location
Membrane.
UNIPROT
Synonyms
CD 49a antibody
CD49 antigen-like family member A antibody
CD49a antibody
CD49a antigen antibody
Integrin alpha-1 antibody
ITA1_HUMAN antibody
Itga 1 antibody
ITGA1 antibody
Laminin and collagen receptor antibody
Very late activation protein 1 antibody
ExpandImages
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Flow cytometric analysis of HeLa cells labeling Integrin alpha 1.
Cells were washed twice with cold PBS and resuspend. Then stained with the primary antibody (HA723594, 1/1,000) (red) compared with Rabbit IgG Isotype Control (green). After incubation of the primary antibody at +4℃ for an hour, the cells were stained with a iFluor™ 488 conjugate-Goat anti-Rabbit IgG Secondary antibody (HA1121) at 1/1,000 dilution for 30 minutes at +4℃. Unlabelled sample was used as a control (cells without incubation with primary antibody; black).
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Products with the same target and pathway
Integrin alpha 1 Rabbit Polyclonal Antibody
Application: WB,FC
Reactivity: Human,Rat
Conjugate: unconjugated
Integrin alpha 1 Recombinant Rabbit Monoclonal Antibody [PSH14-05]
Application: WB,IHC-P
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated
