FAM55C Mouse Monoclonal Antibody [4-E11]
Catalog# M1306-3
FAM55C Mouse Monoclonal Antibody [4-E11]
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WB
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IF-Cell
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Human
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unconjugated
Overview
Product Name
FAM55C Mouse Monoclonal Antibody [4-E11]
Antibody Type
Mouse Monoclonal Antibody
Immunogen
Recombinant protein with Human FAM55C aa 155-429 / 559.
Species Reactivity
Human
Validated Applications
WB, IF-Cell
Molecular Weight
Predicted band size: 64 kDa
Positive Control
Fam55C-GST recombinant protein, NCCIT.
Conjugation
unconjugated
Clone Number
4-E11
RRID
Product Features
Form
Liquid
Concentration
Storage Instructions
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). Store at -20℃ long term.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Isotype
IgG1
Purification Method
Protein A affinity purified.
Application Dilution
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WB
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1:1,000-1:5,000
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IF-Cell
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1:50-1:200
Target
Function
This gene encodes a member of the neurexophilin family of neuropeptide-like glycoproteins. The encoded protein contains a variable N-terminal domain, a highly conserved neurexophilin and PC-esterase (NXPE) central domain, a short linker region, and a cysteine-rich C-terminal domain. This protein binds alpha neurexins, a group of presynaptic transmembrane receptors that promote adhesion between dendrites and axons. Alternative splicing results in multiple transcript variants.
Background References
1. Yamada N et al. Genome-wide DNA methylation analysis in hepatocellular carcinoma. Oncol Rep 35(4):2228-36 (2016).
2. Clark HF et al. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. Genome Res 13(10):2265-70 (2003).
Sequence Similarity
Belongs to the NXPE family.
Subcellular Location
Secreted.
UNIPROT
Synonyms
FA55C_HUMAN antibody
FAM55C antibody
Protein FAM55C antibody
Images
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Western blot analysis of Fam55C on Fam55C-GST recombinant protein lysates using anti-Fam55C antibody at 1/5,000 dilution.
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ICC staining Fam55C in NCCIT cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"