Oxytocin Receptor Rabbit Polyclonal Antibody
Catalog# HA500203
Oxytocin Receptor Rabbit Polyclonal Antibody
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WB
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Human
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Mouse
-
unconjugated
Overview
Product Name
Oxytocin Receptor Rabbit Polyclonal Antibody
Antibody Type
Rabbit Polyclonal Antibody
Immunogen
Synthetic peptide within human Oxytocin Receptor aa 340-375 (Cytoplasmic domain).
Species Reactivity
Human, Mouse
Validated Applications
WB
Molecular Weight
predicted 43 kDa
Positive Control
Mouse uterus tissue lysate, Jurkat cell lysate.
Conjugation
unconjugated
RRID
Product Features
Form
Liquid
Concentration
Storage Instructions
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Storage Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Isotype
IgG
Purification Method
Immunogen affinity purified.
Application Dilution
-
WB
-
1:500-1:2,000
Target
Function
The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition.
Background References
1. Jurek B. et. al. The Oxytocin Receptor: From Intracellular Signaling to Behavior. Physiol Rev. 2018 Jul
2. Arrowsmith S. et. al. Oxytocin: its mechanism of action and receptor signalling in the myometrium. J Neuroendocrinol. 2014 Jun
Subcellular Location
Cell membrane.
Synonyms
OT R antibody
OT-R antibody
OTR 1 antibody
OTR antibody
OTR1 antibody
OXT R antibody
Oxtr antibody
OXYR_HUMAN antibody
Oxytocin receptor antibody
Images
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Western blot analysis of Oxytocin Receptor on different lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody (HA500203, 1/500) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:5,000 dilution was used for 1 hour at room temperature.
Positive control:
Lane 1: Mouse uterus tissue lysate
Lane 2: Jurkat cell lysate
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Alternative Products
Oxytocin Receptor Recombinant Rabbit Monoclonal Antibody [JE34-57]
Application: WB
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated
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