Phospho-AP2M1 (Thr156) Rabbit Polyclonal Antibody
Catalog# ER65961
Phospho-AP2M1 (Thr156) Rabbit Polyclonal Antibody
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WB
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Human
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Mouse
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Rat
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unconjugated
Overview
Product Name
Phospho-AP2M1 (Thr156) Rabbit Polyclonal Antibody
Antibody Type
Rabbit Polyclonal Antibody
Immunogen
Synthesized phosho peptide around human AP2M1 (Thr156)
Species Reactivity
Human, Mouse, Rat
Validated Applications
WB
Molecular Weight
47 kD
Conjugation
unconjugated
Product Features
Form
Liquid
Concentration
Storage Instructions
-15℃ to -25℃/1 year(Do not lower than -25℃)
Storage Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Isotype
IgG
Application Dilution
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WB
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1:1,000-1:2,000
Target
Function
This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Three transcript variants encoding different isoforms have been found for this gene.
Background References
暂无
Subcellular Location
Cell membrane . Membrane, coated pit ; Peripheral membrane protein; Cytoplasmic side. AP-2 appears to be excluded from internalizing CCVs and to disengage from sites of endocytosis seconds before internalization of the nascent CCV.
Images
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Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1,000, 4°over night
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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