Shiga toxin subunit B Rabbit Polyclonal Antibody
Catalog# R1305-1
Shiga toxin subunit B Rabbit Polyclonal Antibody
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WB
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ELISA
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Escherichia coli
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unconjugated
Overview
Product Name
Shiga toxin subunit B Rabbit Polyclonal Antibody
Antibody Type
Rabbit Polyclonal Antibody
Immunogen
Full length protein of shiga toxin subunit B.
Species Reactivity
Escherichia coli
Validated Applications
WB, ELISA
Target Molecular Weight
Predicted band size: 10 kDa
Positive Control
Full length recombinant protein of shiga toxin subunit B
Conjugation
unconjugated
RRID
Product Features
Form
Liquid
Concentration
1 mg/mL.(The concentration of this product may be batch-dependent)
Storage Instructions
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). Store at -20℃ long term.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Isotype
IgG
Purification Method
Immunogen affinity purified.
Application Dilution
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WB
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1:2,000-1:5,000
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ELISA 1
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1,000- 1:5,000
Target
Function
Shiga toxins are a family of related toxins with two major groups, Stx1 and Stx2, whose genes are considered to be part of the genome of lambdoid prophages. Shiga toxin contains a single subunit A and five copies of subunit B. The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli.
Background References
1. Cherla R P, Lee S Y, Tesh V L. Shiga toxins and apoptosis [J]. FEMS Microbiol Lett, 2003, 228:159-166.
2. Leomil L, Aidar-Ugrinovich L, Guth B E, et al. Frequency of Shiga toxin-producing E.coli isolates among diarrheic and non-diarrheic calves in Brazil [J]. Vet Microbiol, 2003, 97:103-109.
Sequence Similarity
Belongs to the StxB family.
Images
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Western blot analysis on full length recombinant protein of shiga toxin subunit B using polyclonal antibody.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"