KLH Rabbit Polyclonal Antibody
Catalog# R1307-6
KLH Rabbit Polyclonal Antibody
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WB
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ELISA
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Species independent
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unconjugated
Overview
Product Name
KLH Rabbit Polyclonal Antibody
Antibody Type
Rabbit Polyclonal Antibody
Immunogen
Recombinant full length protein of Megathura crenulata KLH.
Species Reactivity
Species independent
Validated Applications
WB, ELISA
Target Molecular Weight
Predicted band size: 392 kDa
Positive Control
Full length KLH protein
Conjugation
unconjugated
RRID
Product Features
Form
Liquid
Concentration
1 mg/mL.(The concentration of this product may be batch-dependent)
Storage Instructions
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). Store at -20℃ long term.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Isotype
IgG
Purification Method
Protein A affinity purified.
Application Dilution
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WB
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1:10,000-1:20,000
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ELISA
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1:10,000-1:20,000
Target
Function
Keyhole limpet hemocyanin (KLH) is a large cooper-containing protein consisting of subunits with MW of 400 kDa. It is found in the hemolymph of the sea molluskMegathura crenulata. This?extracellular respiratory protein?has many immunostimulatory properties, including the ability to enhance the host’s immune response by interacting with T cells,?monocytes, macrophages, and polymorphonuclear lymphocytes. Since its discovery, KLH has been used primarily as a carrier for vaccines and antigens and as adjuvant treatment in regimens such as antimicrobial therapy.
Background References
1. Harris JR, Markl J. Keyhole limpet hemocyanin (KLH): a biomedical review. Micron.1999;30 (6): 597–623.
2. Aarntzen EH, de Vries, IJ, Goertz JH et al. Humoral anti-KLH responses in cancer patients treated with dendritic cell-based immunotherapy are dictated by different vaccination parameters. Cancer Immunol Immunother.
Synonyms
Hemocyanin 2 c chain antibody
Hemocyanin 2c chain antibody
Hemocyanin A chain antibody
Hemocyanin B chain antibody
Keyhole limpet hemocyanin antibody
KLH A antibody
KLH B antibody
KLH2 c antibody
KLH2c antibody
KLHA antibody
ExpandImages
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Western blot analysis on full length KLH protein using anti-KLH polyclonal antibody
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"