BMPR1A Rabbit Polyclonal Antibody (R1510-1)
Catalog# R1510-1
Rabbit Polyclonal to BMPR1A
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WB
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IF-Cell
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IHC-P
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FC
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Human
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Mouse
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Rat
Specifications
Product Type
Rabbit polyclonal primary
Product Name
BMPR1A Rabbit Polyclonal Antibody (R1510-1)
Immunogen
Recombinant protein within human bmpr1a aa 11-180/532.
Host
Rabbit
Positive Control
293 cell lysates, Hela, HepG2, SKOV-3, human liver carcinoma tissue, human kidney tissue, mouse skeletal muscle tissue, mouse smooth muscle tissue, mouse kidney tissue, Jurkat.
Conjugation
Unconjugated
Clonality
Polyclonal
RRID
APPLICATION DILUTION
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WB
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1:1,000
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IF-Cell
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1:50-1:200
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IHC-P
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1:50-1:200
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FC
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1:50-1:100
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1ug/ul
Purification
Immunogen affinity purified.
Molecular Weight
Predicted band size: 60 kDa
Isotype
IgG
TARGET
UNIPROT #
PROTEIN NAME
BMPR1A
SYNONYMS
10q23del antibody;Activin A receptor type II like kinase 3 antibody;Activin receptor like kinase 3 antibody;Activin receptor-like kinase 3 antibody;ACVRLK 3 antibody;ACVRLK3 antibody;ALK 3 antibody;ALK-3 antibody;ALK3 antibody;BMP type-1A receptor antibody;BMPR 1A antibody;Bmpr antibody;BMPR-1A antibody;Bmpr1a antibody;BMR1A_HUMAN antibody;Bone morphogenetic protein receptor type IA antibody;Bone morphogenetic protein receptor type IA precursor antibody;Bone morphogenetic protein receptor type-1A antibody;BR 1a antibody;BR1a antibody;CD 292 antibody;CD292 antibody;CD292 antigen antibody;EC 2.7.11.30 antibody;Serine threonine protein kinase receptor R5 antibody;Serine threonine protein kinase receptor R5 precursor antibody;Serine/threonine-protein kinase receptor R5 antibody;SKR 5 antibody;SKR5 antibody;zBMPR IA antibody;zBMPRIA antibody
SEQUENCE SIMILARITIES
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
TISSUE SPECIFICITY
Highly expressed in skeletal muscle.
POST-TRANSLATIONAL MODIFICATION
Glycosylated.
SUBCELLULAR LOCATION
Cell membrane.
FUNCTION
Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Two type I receptors have been characterized, BMPR-IA (also designated SKR5, ALK-3, and BRK-1) and BMPR-IB (also designated ALK-6 and SKR 6), that bind to bone morphogenetic proteins (BMP)-2, BMP-4, and osteogenic protein (OP)-1 (also designated BMP-7). BMPR-IA and BMPR-IB are both expressed in human glioma cell lines. The type II receptor, BMPR-II, efficiently binds to OP-1 and BMP-2 and weakly binds BMP-4, and it is widely expressed in different tissues, including brain. The BMP receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morphogenesis in a dose dependent fashion.
CITATIONS
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Yuling Mi; Caiqiao Zhang
The Attenuating Effect of the Intraovarian Bone Morphogenetic Protein 4 on Age-Related Endoplasmic Reticulum Stress in Chicken Follicular Cells
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WB
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IHC
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IF
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hen
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Citation
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Lei, S. S., Huang, X. W., Li, L. Z., Wang, X. P., Zhang, Y., Li, B., & Shou, D.
Explorating the mechanism of Epimedii folium-Rhizoma drynariae herbal pair promoted bone defects healing through network pharmacology and experimental studies
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IHC
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Rat
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Citation
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Total Flavonoids from Rhizoma Drynariae (Gusuibu) Alleviates Diabetic Osteoporosis by Activating BMP2/Smad Signaling Pathway
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IHC
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Rat
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Citation
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