Uridine Phosphorylase 1 Recombinant Rabbit Monoclonal Antibody [JE56-62]
Catalog# HA720018
Uridine Phosphorylase 1 Recombinant Rabbit Monoclonal Antibody [JE56-62]
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WB
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Human
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Mouse
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Rat
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unconjugated
Overview
Product Name
Uridine Phosphorylase 1 Recombinant Rabbit Monoclonal Antibody [JE56-62]
Antibody Type
Recombinant Rabbit monoclonal Antibody
Immunogen
Synthetic peptide within human Uridine Phosphorylase 1 aa 1-50.
Species Reactivity
Human, Mouse, Rat
Validated Applications
WB
Molecular Weight
Predicted band size: 34 kDa
Positive Control
A431 cell lysate, mouse kidney tissue lysate, rat lung tissue lysate, rat kidney tissue lysate.
Conjugation
unconjugated
Clone Number
JE56-62
RRID
Product Features
Form
Liquid
Concentration
Storage Instructions
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Storage Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Isotype
IgG
Purification Method
Protein A affinity purified.
Application Dilution
-
WB
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1:500-1:2,000
Target
Function
This gene encodes a uridine phosphorylase, an enzyme that catalyzes the reversible phosphorylation of uridine (or 2'- deoxyuridine) to uracil and ribose-1-phosphate (or deoxyribose-1-phosphate). The encoded enzyme functions in the degradation and salvage of pyrimidine ribonucleosides.
Background References
1. Guan Y. et. al. Uridine phosphorylase 1 associates to biological and clinical significance in thyroid carcinoma cell lines. J Cell Mol Med. 2019 Nov
2. Bhasin N. et. al. Vitamin D Regulation of the Uridine Phosphorylase 1 Gene and Uridine-Induced DNA Damage in Colon in African Americans and European Americans. Gastroenterology. 2018 Oct
Subcellular Location
Cytosol, nucleoplasm.
Synonyms
UDRPASE antibody
UP antibody
UPase 1 antibody
UPASE antibody
UPP antibody
Upp1 antibody
UPP1_HUMAN antibody
UrdPase 1 antibody
Uridine phosphorylase 1 antibody
Images
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Western blot analysis of Uridine Phosphorylase 1 on different lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody (HA720018, 1/500) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:5,000 dilution was used for 1 hour at room temperature.
Positive control:
Lane 1: A431 cell lysate
Lane 2: Mouse kidney tissue lysate
Lane 3: Rat lung tissue lysate
Lane 4: Rat kidney tissue lysate
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"