Tbx3 Rabbit Polyclonal Antibody
Catalog# R1306-4
Tbx3 Rabbit Polyclonal Antibody
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WB
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Human
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Mouse
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Rat
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unconjugated
Overview
Product Name
Tbx3 Rabbit Polyclonal Antibody
Antibody Type
Rabbit Polyclonal Antibody
Immunogen
Synthetic peptide within mouse TBX3 aa 401-445.
Species Reactivity
Human, Mouse, Rat
Validated Applications
WB
Molecular Weight
Predicted band size: 79 kDa
Positive Control
MCF-7, PC12, Hela, 293T, NIH/3T3, F9
Conjugation
unconjugated
RRID
Product Features
Form
Liquid
Concentration
Storage Instructions
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). Store at -20℃ long term.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Isotype
IgG
Purification Method
Immunogen affinity purified.
Application Dilution
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WB
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1:1,000
Target
Function
T-box transcription factor TBX3 is a protein that in humans is encoded by the TBX3 gene.This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Defects in TBX3 are the cause of ulnar-mammary syndrome (UMS). UMS is characterized by ulnar ray defects, obesity, hypogenitalism, delayed puberty, hypoplasia of nipples and apocrine glands
Background References
1. "An ancient family of embryonically expressed mouse genes sharing a conserved protein motif with the T locus." Bollag R.J., Siegfried Z., Cebra-Thomas J.A., Garvey N., Davison E.M., Silver L.M. Nat. Genet. 7:383-389(1994).
2. "Structure of the DNA-bound T-box domain of human TBX3, a transcription factor responsible for ulnar-mammary syndrome." Coll M., Seidman J.G., Muller C.W. Structure 10:343-356(2002).
Tissue Specificity
Widely expressed.
Subcellular Location
Nucleus.
UNIPROT
Synonyms
Bladder cancer related protein XHL antibody
T box 3 antibody
T-box protein 3 antibody
T-box transcription factor TBX3 antibody
Tbx3 antibody
TBX3 ISO antibody
TBX3_HUMAN antibody
UMS antibody
XHL antibody
Images
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Western blot analysis on different cell lysates using anti-TBX3 rabbit polyclonal antibodies.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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