Thyroid Peroxidase(TPO) Mouse Monoclonal Antibody [PT0857]
Catalog# EM60134
Thyroid Peroxidase(TPO) Mouse Monoclonal Antibody [PT0857]
-
WB
-
Human
-
unconjugated
Overview
Product Name
Thyroid Peroxidase(TPO) Mouse Monoclonal Antibody [PT0857]
Antibody Type
Mouse Monoclonal Antibody
Immunogen
Synthesized peptide derived from human Thyroid Peroxidase(TPO)
Species Reactivity
Human
Validated Applications
WB
Molecular Weight
103 kDa
Positive Control
Glandular pool- thyroid, Spleen, Thyroid.
Conjugation
unconjugated
Clone Number
PT0857
Product Features
Form
Liquid
Concentration
Storage Instructions
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method
Immunogen affinity purified.
Application Dilution
-
WB
-
1:500-1:2000
Target
Function
This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined.
Background References
暂无
Subcellular Location
Membrane.
UNIPROT
Synonyms
MSA antibody
PERT_HUMAN antibody
TDH2A antibody
Thyroid microsomal antigen antibody
Thyroid peroxidase antibody
Thyroperoxidase antibody
TPO antibody
TPX antibody
Images
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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