ATP1A2 Recombinant Rabbit Monoclonal Antibody [JE34-00] (HA721422)

UNIPROT #

P50993

PROTEIN NAME

ATP1A2

SYNONYMS

AT1A2_HUMAN antibody;Atp1a2 antibody;FHM2 antibody;KIAA0778 antibody;MHP2 antibody;Na(+)/K(+) ATPase alpha-2 subunit antibody;Na+/K+ ATPase alpha 2 subunit antibody;Sodium potassium ATPase antibody;Sodium pump subunit alpha 2 antibody;Sodium pump subunit alpha-2 antibody;Sodium/potassium transporting ATPase alpha 2 chain antibody;Sodium/potassium transporting ATPase subunit alpha 2 antibody;Sodium/potassium-transporting ATPase subunit alpha-2 antibody

SUBCELLULAR LOCATION

Cell membrane.

FUNCTION

Sodium/potassium-transporting ATPase subunit alpha-2 is a protein which in humans is encoded by the ATP1A2 gene. The protein encoded by this gene belongs to the family of P-type cation transport ATPases and to the subfamily of Na+/K+-ATPases. Na+/K+-ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+-ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit.