Catalase Rabbit Polyclonal Antibody (ER40125)
Catalog# ER40125
Rabbit Polyclonal to Catalase
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WB
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IHC-P
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Human
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Mouse
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Rat
Positive control:
Lane 1: F9 cell lysate
Lane 2: A549 cell lysate
Lane 3: Mouse lung tissue lysate
Lane 4: Mouse liver tissue lysate
Lane 5: Human lung tissue lysate
Lane 6: Hela cell lysate
Specifications
Product Type
Rabbit polyclonal primary
Product Name
Catalase Rabbit Polyclonal Antibody (ER40125)
Immunogen
Synthetic peptide within c-terminal human catalase.
Host
Rabbit
Positive Control
F9 cell lysate, A549 cell lysate, Mouse lung tissue lysate, Mouse liver tissue lysate, Human lung tissue lysate, Hela cell lysate, human liver tissue, rat kidney tissue, rat liver tissue, rat lung tissue, mouse liver tissue, mouse kidney tissue.
Conjugation
Unconjugated
Clonality
Polyclonal
RRID
APPLICATION DILUTION
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WB
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1:1,000
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IHC-P
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1:200
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1ug/ul
Purification
Immunogen affinity purified.
Molecular Weight
Predicted band size: 60 kDa
Isotype
IgG
TARGET
UNIPROT #
PROTEIN NAME
Catalase
SYNONYMS
Cas1 antibody;CAT antibody;CATA_HUMAN antibody;Catalase antibody;Cs1 antibody;MGC138422 antibody;MGC138424 antibody
SEQUENCE SIMILARITIES
Belongs to the catalase family.
POST-TRANSLATIONAL MODIFICATION
The N-terminus is blocked.
SUBCELLULAR LOCATION
Peroxisome.
FUNCTION
Hydrogen peroxide is a harmful byproduct of many normal metabolic processes; to prevent damage to cells and tissues, it must be quickly converted into other, less dangerous substances. To this end, catalase is frequently used by cells to rapidly catalyze the decomposition of hydrogen peroxide into less-reactive gaseous oxygen and water molecules. Catalase is usually located in a cellular, bipolar environment organelle called the peroxisome. All known animals use catalase in every organ, with particularly high concentrations occurring in the liver. Catalase promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
CITATIONS
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Kairui Zhang and Bin Yu
High cholesterol inhibits tendon-related gene expressions in tendon-derived stem cells through reactive oxygen species-activated nuclear factor-κB signaling. Journal of cellular physiology, 234(10), 18017–18028.
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WB
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IHC
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Mouse
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Citation
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Ma, W., Jia, L., Xiong, Q., & Du, H.
Iron Overload Protects from Obesity by Ferroptosis
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WB
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Mouse
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Citation
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Jiang, H., Chen, F., Song, D., Zhou, X., Ren, L., & Zeng, M.
Dynamin-Related Protein 1 Is Involved in Mitochondrial Damage, Defective Mitophagy, and NLRP3 Inflammasome Activation Induced by MSU Crystals
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WB
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Mouse
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Citation
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Membrane damage during ferroptosis is caused by oxidation of phospholipids catalyzed by the oxidoreductases POR and CYB5R1
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WB
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Human
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Citation
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