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DOT1L Recombinant Rabbit Monoclonal Antibody [PSH01-57] (HA721700)

Price: Regular price $385.00

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Catalog# HA721700

Rabbit Monoclonal to DOT1L

Tested for

  • WB

  • IHC-P

Reacts with

  • Human

  • Mouse

  • Rat

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

DOT1L Recombinant Rabbit Monoclonal Antibody [PSH01-57] (HA721700)

Immunogen

Recombinant protein within human dot1/kmt4 aa 1- 500.

Host

Rabbit

Positive Control

K-562 cell lysate, THP-1 cell lysate, HeLa cell lysate, 293T cell lysate, human testis tissue, mouse testis tissue, rat testis tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

PSH01-57

RRID

AB_3072813

APPLICATION DILUTION

  • WB

  • 1:1,000

  • IHC-P

  • 1:200-1:1,000

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 165 kDa

Isotype

IgG

TARGET

UNIPROT #

Q8TEK3

PROTEIN NAME

DOT1L

SYNONYMS

Disrupter of telomere silencing protein 1 antibody;DOT 1 antibody;DOT1 antibody;DOT1 like antibody;DOT1 like histone H3 methyltransferase (S. cerevisiae) antibody;DOT1 like histone H3 methyltransferase antibody;DOT1 like histone H3K79 methyltransferase antibody;DOT1 like protein antibody;DOT1, S. cerevisiae, homolog of antibody;DOT1-like protein antibody;DOT1L antibody;DOT1L_HUMAN antibody;EC 2.1.1.43 antibody;H3 K79 HMTase antibody;H3 lysine-79 specific antibody;H3-K79-HMTase antibody;Histone H3 K79 methyltransferase antibody;Histone H3 methyltransferase antibody;Histone H3 methyltransferase DOT1-like antibody;Histone H3-K79 methyltransferase antibody;Histone lysine N methyltransferase H3 lysine 79 specific antibody;Histone methyltransferase DOT1L antibody;Histone-lysine N-methyltransferase antibody;KIAA1814 antibody;KMT4 antibody;Lysine N methyltransferase 4 antibody;Lysine N-methyltransferase 4 antibody

SUBCELLULAR LOCATION

Nucleus.

FUNCTION

Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.

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