DYKDDDDK Tag ( FLAG ) Mouse Monoclonal Antibody [A2-A4] (M1403-2)

Ubiquitin-conjugating enzyme UBE2O regulates cellularclock function by promoting the degradation of thetranscription factor BMAL1

Chen, R., Huang, M., Yang, X., Chen, X. H., Shi, M. Y., Li, Z. F., Chen, Z. N., & Wang, K.

CALR-TLR4 Complex Inhibits Non-Small Cell Lung Cancer Progression by Regulating the Migration and Maturation of Dendritic Cells

Yang Yanfang,et al

SUMOylation of annexin A6 retards cell migration and tumor growth by suppressing RHOU/AKT1-involved EMT in hepatocellular carcinoma

Wang, J., Huang, Z., Huang, P., Wang, Q., Li, Y., Liu, X. H., Lin, F. C., & Lu, J.

The Plant Homeodomain Protein Clp1 Regulates Fungal Development, Virulence, and Autophagy Homeostasis in Magnaporthe oryzae

miR-23a regulates the disease resistance of grass carp (Ctenopharyngodon idella) by targeting autophagy-related genes, ATG3 and ATG12

Xueli Bai * Tingbo Liang

Primary tumor-derived exosomes facilitate metastasis by regulating adhesion of circulating tumor cells via SMAD3 in liver cancer

Plaat1 promotes P53 degradation Via autophagy-lysosome pathway in zebrafish

He, Y., Wang, X., Lu, W., Zhang, D., Huang, L., Luo, Y., Xiong, L., Li, H., Zhang, P., Li, Q., & Liang, S.

PGK1 contributes to tumorigenesis and sorafenib resistance of renal clear cell carcinoma via activating CXCR4/ERK signaling pathway and accelerating glycolysis

Xin H, Tang Y, Jin YH, et al

Knockdown of LMNA inhibits Akt/β-catenin-mediated cell invasion and migration in clear cell renal cell carcinoma cells

A VASt-domain protein regulates autophagy, membrane tension, and sterol homeostasis in rice blast fungus

Jie Wu ;Ayaz Najafov;Hongguang Xia

Pharmacological targeting of MCL-1 promotes mitophagy and improves disease pathologies in an Alzheimer’s disease mouse model

Wang, K., Huang, W., Chen, R., Lin, P., Zhang, T., Ni, Y. F., Li, H., Wu, J., Sun, X. X., Geng, J. J., Zhu, Y. M., Nan, G., Zhang, W., Chen, X., Zhu, P., Bian, H., & Chen, Z. N.

Di-methylation of CD147-K234 promotes the progression of NSCLC by enhancing lactate export

Guoqiang Xu

A Mental Retardation-linked Nonsense Mutation in Cereblon Is Rescued by Proteasome Inhibition

Jiao Liu,et al

Comprehensive screening of industrially relevant components at genome scale using a high-quality gene overexpression collection of Corynebacterium glutamicum

Qian, H., Sun, L., Wu, M., Zhao, W., Liu, M., Liang, S., Zhu, X., Li, L., Su, Z., Lu, J., Lin, F., & Liu, X.

The COPII subunit MoSec24B is involved in development, pathogenicity and autophagy in the rice blast fungus

The kinase CIPK11 functions as a positive regulator in cadmium stress response in Arabidopsis

Guoqiang Xu

Quantitative proteomics and biochemical analyses reveal the role of endoplasmin in the regulation of the expression and secretion of A Disintegrin And Metalloproteinase 12

Dahai Yang,Qin Liu

Novel T3SS effector EseK in Edwardsiella piscicida is chaperoned by EscH and EscS to express virulence

Cai, Y. Y., Wang, J. Y., Wu, X. Y., Liang, S., Zhu, X. M., Li, L., Lu, J. P., Liu, X. H., & Lin, F. C.

MoOpy2 is essential for fungal development, pathogenicity, and autophagy in Magnaporthe oryzae

Qu, Y., Wang, J., Huang, P., Liu, X., Lu, J., & Lin, F. C.

PoRal2 Is Involved in Appressorium Formation and Virulence via Pmk1 MAPK Pathways in the Rice Blast Fungus Pyricularia oryzae

A kelch domain cell end protein, PoTea1, mediates cell polarization during appressorium morphogenesis in Pyricularia oryzae

PLAAT1 inhibits type I interferon response via degradation of IRF3 and IRF7 in Zebrafish

HMMR alleviates endoplasmic reticulum stress by promoting autophagolysosomal activity during endoplasmic reticulum stress‐driven hepatocellular carcinoma progression

Integrative omic analysis reveals the improvement of alkaloid accumulation by ultraviolet-B radiation and its upstream regulation in Catharanthus roseus

Qin Liu

The Edwardsiella piscicida thioredoxin-like protein inhibits ASK1-MAPKs signaling cascades to promote pathogenesis during infection.

Jiang, J., Li, Y., Sun, Z., Gong, L., Li, X., Shi, F., Yao, J., Meng, Y., Meng, X., Zhang, Q., Wang, Y., Su, X., & Diao, H.

LncNSPL facilitates influenza A viral immune escape by restricting TRIM25-mediated K63-linked RIG-I ubiquitination

Azelnidipine inhibits esophageal squamous cell carcinoma proliferation in vivo and in vitro by targeting MEK1/2

Zhou, D., Yan, H., Yang, S., Zhang, Y., Xu, X., Cen, X., Lei, K., & Xia, H.

SC75741, A Novel c-Abl Inhibitor, Promotes the Clearance of TDP25 Aggregates via ATG5-Dependent Autophagy Pathway

Yang, Y., Song, L., Huang, X., Feng, Y., Zhang, Y., Liu, Y., Li, S., Zhan, Z., Zheng, L., Feng, H., & Li, Y.

PRPS1-mediated purine biosynthesis is critical for pluripotent stem cell survival and stemness. Aging, 13(3), 4063–4078.

Homeostasis of Arabidopsis R protein RPS2 is negatively regulated by the RING-type E3 ligase MUSE16

MoFap7, a ribosome assembly factor, is required for fungal development and plant colonization of Magnaporthe oryzae

Jin, X., Li, L., Peng, Q., Gan, C., Gao, L., He, S., Tan, S., Pu, W., Liu, Y., Gong, Y., Yao, Y., Wang, G., Liu, X., Gong, M., Lei, P., Zhang, H., Qi, S., Xu, H., Hu, H., Dong, B., … Dai, L.

Glycyrrhetinic acid restricts mitochondrial energy metabolism by targeting SHMT2

Jiyong Zhou,Jinyan Gu

Identification and function analysis of canine stimulator of interferon gene (STING)

Genome-editing prodrug: Targeted delivery and conditional stabilization of CRISPR-Cas9 for precision therapy of inflammatory disease

Li, X., Li, H., Jing, Q., Wang, M., Hu, T., Li, L., Zhang, Q., Liu, M., Fu, Y. V., Han, J., & Su, D.

Structural insights into multifunctionality of human FACT complex subunit hSSRP1

Yan, Y. Q., Zheng, R., Liu, Y., Ruan, Y., Lin, Z. H., Xue, N. J., Chen, Y., Zhang, B. R., & Pu, J. L.

Parkin regulates microglial NLRP3 and represses neurodegeneration in Parkinson's disease

The E3 ubiquitin ligase STUB1 attenuates cell senescence bypromoting the ubiquitination and degradation of the corecircadian regulator BMAL1

Identification of multifunctionality of grass carp (Ctenopharyngodon idella) TBK1 during bacterial infection

Huang, W., Zhao, X., Ji, N., Guo, J., Feng, J., Chen, K., Wu, Y., Wang, J., Feng, H., & Zou, J.

IRF2 Cooperates with Phosphoprotein of Spring Viremia of Carp Virus to Suppress Antiviral Response in Zebrafish

Wang, Q., Wang, J., Huang, P., Huang, Z., Li, Y., Liu, X., Lin, F., & Lu, J.

Nucleosome Assembly Protein 1, Nap1, Is Required for the Growth, Development, and Pathogenicity of Magnaporthe oryzae

A novel cascade allows Metarhizium robertsii to distinguish cuticle and hemocoel microenvironments during infection of insects

ANKRD22, a novel tumor microenvironment-induced mitochondrial protein promotes metabolic reprogramming of colorectal cancer cells

MrSt12 implicated in the regulation of transcription factor AFTF1 by Fus3-MAPK during cuticle penetration by the entomopathogenic fungus Metarhizium robertsii.

Jiemin Wong

Negative regulation of DNMT3A de novo DNA methylation by frequently overexpressed UHRF family proteins as a mechanism for widespread DNA hypomethylation in cancer

IL-27 suppresses spring viremia of carp virus replication in zebrafish

Ding S, Lv J, Hu Z, et al

Phytosulfokine peptide optimizes plant growth and defense via glutamine synthetase GS2 phosphorylation in tomato

A Novel Nitrogen and Carbon Metabolism Regulatory Cascade Is Implicated in Entomopathogenicity of the Fungus Metarhizium robertsii

Zhenglong Guo,et al

Novel biallelic variants in IREB2 cause an early-onset neurodegenerative disorder in a Chinese pedigree

Gao, Y., Xiang, D., Li, W., Zheng, X., Wang, L., Li, Z., & Chen, T.

BRAFV600E Mutation-Responsive miRNA-222-3p Promotes Metastasis of Papillary Thyroid Cancer Cells via Snail-Induced EMT

Cand2 Inhibits CRL-mediated Ubiquitination and Suppresses Autophagy to Facilitate Pathogenicity of Phytopathogenic Fungi

Haruhiko Koseki& Jiemin Wong

UHRF1 targets DNMT1 for DNA methylation through cooperative binding of hemi-methylated DNA and methylated H3K9

Huang, P., Li, Y., Wang, J., Wang, Q., Huang, Z., Liu, X., Lin, F., & Lu, J.

Casein Kinase 2 Mediates Degradation of Transcription Factor Pcf1 during Appressorium Formation in the Rice Blast Fungus

Di Wang

Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome

Nuplazid suppresses esophageal squamous cell carcinoma growth in vitro and in vivo by targeting PAK4

Li, J., Wang, K., Zhang, Y., Qi, T., Yuan, J., Zhang, L., Qiu, H., Wang, J., Yang, H. T., Dai, Y., Song, Y., & Chang, X.

Therapeutic Exon Skipping via a CRISPR-guided Cytidine Deaminase Rescues Dystrophic Cardiomyopathy In Vivo

Zebrafish SETD3 mediated ubiquitination of phosphoprotein limits spring viremia of carp virus infection.

Therapeutic inhibition of PPARα-HIF1α-PGK1 signaling targets leukemia stem and progenitor cells in acute myeloid leukemia

Molecular mechanism of c-Myc and PRPS1/2 against thiopurine resistance in Burkitt's lymphoma

Xu Xiaoyan,et al

Hsc70 promotes anti-tumor immunity by targeting PD-L1 for lysosomal degradation

Kai Wang

Human tumor necrosis factor (TNF)-alpha-induced protein 8-like 2 suppresses hepatocellular carcinoma metastasis through inhibiting Rac1

Wei, X., Zheng, Z., Feng, Z., Zheng, L., Tao, S., Zheng, B., Huang, B., Zhang, X., Liu, J., Chen, Y., Zong, W., Shan, Z., Fan, S., Chen, J., & Zhao, F.

Sigma-1 receptor attenuates osteoclastogenesis by promoting ER-associated degradation of SERCA2