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MEIS1 Recombinant Rabbit Monoclonal Antibody [JA13-26] (ET1704-84)

Price: Regular price $385.00

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Catalog# ET1704-84

Rabbit Monoclonal to MEIS1

Tested for

  • WB

  • IP

  • FC

Reacts with

  • Human

  • Mouse

  • Rat

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

MEIS1 Recombinant Rabbit Monoclonal Antibody [JA13-26] (ET1704-84)

Immunogen

Synthetic peptide within human meis1 aa 328-377 / 390.

Host

Rabbit

Positive Control

Human skeletal muscle tissue lysate, mouse brain tissue lysate, K562.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

JA13-26

RRID

AB_3070527

APPLICATION DILUTION

  • WB

  • 1:500-1:2,000

  • FC

  • 1:50-1:100

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

47 kDa

Isotype

IgG

TARGET

UNIPROT #

O00470

PROTEIN NAME

MEIS1

SYNONYMS

Homeo box protein Meis1 antibody;Homeobox protein Meis1 antibody;Leukemogenic homolog protein antibody;MEIS 1 antibody;Meis homeo box 1 antibody;Meis homeobox 1 antibody;Meis1 antibody;Meis1 mouse homolog antibody;Meis1 myeloid ecotropic viral integration site 1 homolog antibody;Meis1 myeloid ecotropic viral integration site 1 homolog mouse antibody;MEIS1 protein antibody;MEIS1_HUMAN antibody;MGC43380 antibody;Myeloid ecotropic viral integration site 1 homolog antibody;WUGSC:H NH0444B04.1 antibody

SEQUENCE SIMILARITIES

Belongs to the TALE/MEIS homeobox family.

TISSUE SPECIFICITY

Expressed at low level in normal immunohepatopoietic tissues, including the fetal liver. Expressed in a subset of myeloid leukemia cell lines, with the highest expression seen in those with a megakaryocytic-erythroid phenotype. Also expressed at high levels in the cerebellum.

SUBCELLULAR LOCATION

Nucleus.

FUNCTION

Acts as a transcriptional regulator of PAX6. Acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2. Required for hematopoiesis, megakaryocyte lineage development and vascular patterning. May function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias.

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